Propylparaben

Manufactured by Loba Chemie

Sourced in India

Propylparaben is a preservative commonly used in various personal care and cosmetic products. It is a chemical compound with the formula C10H12O3. Propylparaben functions as an antimicrobial agent, helping to prevent the growth of bacteria, fungi, and mold in the products it is used in.

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Lab products found in correlation

Methylparaben, by Loba Chemie (5 mentions) Triethanolamine, by Loba Chemie (2 mentions) Carbopol 934, by Loba Chemie (2 mentions) Clove oil, by Loba Chemie (1 mentions) Mineral oil, by Loba Chemie (1 mentions) Span 80, by Loba Chemie (1 mentions) Tween 80, by Loba Chemie (1 mentions) Propylene glycol, by Loba Chemie (1 mentions) Phospholipon 80 h, by Lipoid (1 mentions) Compritol 888 ato, by Gattefosse (1 mentions) Glycerol monostearate, by Gattefosse (1 mentions) Tefose 63, by Gattefosse (1 mentions) Potassium dihydrogen phosphate, by Loba Chemie (1 mentions) Methanol, by BD (1 mentions) Fluconazole, by Maclin Biochemical Technology (1 mentions) Hydrochloric acid (hcl), by Loba Chemie (1 mentions)

6 protocols using propylparaben

Formulation and Evaluation of Capsaicin Topical Gel

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Capsaicin was obtained from Plant Lipids Private Limited, Telangana, India. Mineral oil, clove oil, Carbopol 934, Tween 80, Span 80, triethanolamine, propylene glycol, methylparaben, propylparaben, and liquid paraffin were purchased from Loba Chemie, Mumbai. All the other chemicals were procured from HiMedia Lab, Mumbai, India. All the solvents were of High-Performance Liquid Chromatography (HPLC) grade.

Rompicherla N.C., Joshi P., Shetty A., Sudhakar K., Amin H.I., Mishra Y., Mishra V., Albutti A, & Alhumeed N. (2022). Design, Formulation, and Evaluation of Aloe vera Gel-Based Capsaicin Transemulgel for Osteoarthritis. Pharmaceutics, 14(9), 1812.

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Lipid-based Nanoparticle Formulation Development

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MF was gifted by Centaur Pharmaceuticals, Mumbai. Glycerol monostearate (GMS), Compritol 888 ATO, Apifil, Tefose-63 and Emulcire were gifted by Gattefosse India Pvt. Ltd., Mumbai. Cetyl palmitate, Syncrowax-HRC, Syncrowax-HGL were gifted by Croda Chemicals, Mumbai. Stearic acid, Tween-80 from Lubrizol, Mumbai and Phospholipon-80 H, Lipoid S-75 (Soya Lecithin) from Lipoid, Germany were gift samples. Ethanol, Acetone and Carbopol 974p were purchased from Research Lab Fine Chem., industries, Mumbai. Methyl paraben, Propyl paraben, Triethanolamine were purchased from Loba Chemie Pvt. Ltd, Mumbai.

Madan J.R., Khude P.A, & Dua K. (2014). Development and evaluation of solid lipid nanoparticles of mometasone furoate for topical delivery. International Journal of Pharmaceutical Investigation, 4(2), 60-64.

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Soybean Phytochemical Extraction and Profiling

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Soybean, G. max (L.) Merrill family Fabaceae, was obtained from Haraz, Babb El-Khalk, Egypt, and kindly authenticated by Professor Dr Mohamed El-Gebaly, Taxonomy Specialist at El-Orman Botanical Garden, Giza, Egypt; methanol and acetonitrile (high-performance liquid chromatography [HPLC] grade; Cornell Lab, Cairo, Egypt); standard soy saponin B (Wako Pure Chemical Industries, Osaka, Japan); PC (Sigma-Aldrich Co., St Louis, MA, USA); methylparaben (EL-Gomhouria Co., Cairo, Egypt); polyethylene glycol (PEG 400), hydroxypropyl methylcellulose (HPMC) (E 50 LV), Pluronic F127 (Poloxamer407), propylparaben (LOBA Chemie, India); dimethyl sulfoxide (DMS), n-hexane, ethanol (ADWIC; El-Nasr Pharmaceutical Chemicals Co., Egypt); cellophane membrane (12,000–14,000 Dalton molecular weight; El-Maadi Co., Cairo, Egypt).

El-Menshawe S.F., Ali A.A., Rabeh M.A, & Khalil N.M. (2018). Nanosized soy phytosome-based thermogel as topical anti-obesity formulation: an approach for acceptable level of evidence of an effective novel herbal weight loss product. International Journal of Nanomedicine, 13, 307-318.

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Formulation and Characterization of Pectin-Based Gel

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Edible-grade sucrose was purchased from the local grocery store. Pectin (Sweet King India L.L.P, New Delhi, India), citric acid (Central Drug House (P) Ltd., New Delhi, India), olive oil (Ruchi Food Line, Cuttack, Odisha, India), methylparaben (Loba Chemie, Mumbai, India), and propylparaben (Loba Chemie, Mumbai, India) were purchased. Preservative water (PW) was prepared by dissolving methylparaben (C₈H₈O₃; 0.5% w/w) and propylparaben (C₁₀H₁₂O₃; 0.05% w/w) in distilled water at 60 °C.

Dhal S., Pal A., Gramza-Michalowska A., Kim D., Mohanty B., Sagiri S.S, & Pal K. (2023). Formulation and Characterization of Emulgel-Based Jelly Candy: A Preliminary Study on Nutraceutical Delivery. Gels, 9(6), 466.

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Antifungal Topical Formulation Development

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Fluconazole (Macklin, China), HPMC E5 LV, methyl paraben, propyl paraben, hydrochloric acid, potassium dihydrogen phosphate (Loba Chemie, India), xanthan gum (Titan Biotech, India), polyethylene sorbitan monooleate (tween 80), clove oil (Molychem, India), sorbitan monolaurate (span 20) (Acros Organics, USA), cinnamon leaf oil (Deo Organics, Sri Lanka), palm olein (raffles oil, Nigeria), methanol (BDH, UK), Strat-M™ membrane, 0.45 μm (Millipore, UK), filter units (0.45 μm), Candida albicans (clinical isolate grown at 37 °C for 24 h on Sabouraud dextrose agar), and deionised water.

Ogedengbe O.T, & Kolawole O.M. (2024). Formulation and evaluation of fluconazole emulgels for potential treatment of vaginal candidiasis. Heliyon, 10(6), e28206.

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Silymarin-based Topical Formulation Development

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The Serum Institute of India Pvt. Ltd. Pune, India supplied silymarin. Carbopol 934, methyl paraben and propyl paraben were purchased from Loba Chemie Pvt. Ltd. Mumbai, India. Propylene glycol and triethanolamine were obtained from SRL Chemicals Pvt. Ltd. Chennai, India.

Venugopal D.C., Senthilnathan R.D., Maanvizhi S., Madhavan Y., Sankarapandian S., Ramshankar V, & Kalachaveedu M. (2023). Preparation and Characterization of Silymarin Gel: A Novel Topical Mucoadhesive Formulation for Potential Applicability in Oral Pathologies. Gels, 9(2), 139.

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