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Ingenia mri

Manufactured by Philips

The Ingenia MRI is a magnetic resonance imaging (MRI) system manufactured by Philips. It is designed to provide high-quality medical imaging for healthcare professionals. The core function of the Ingenia MRI is to generate detailed images of the body's internal structures using strong magnetic fields and radio waves.

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13 protocols using ingenia mri

1

DWI Acquisition for Hepatic Tumor Imaging

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This study was approved by the Institutional Review Board. The written informed consent documents were obtained from 106 healthy participants and 10 patients who had hepatic tumors. Participants underwent scans using a 3T Philips Ingenia MRI system (Philips Healthcare, Best, the Netherlands) containing an eight-channel coil. Two breath-hold DW imaging acquisitions were done for b values of 0 and 800 with the following parameters: single-shot spin-echo EPI; repetition time (TR)/echo time (TE) of 4000/55 ms; matrix size of 336×336; field of view (FOV) of 360×360 mm; the number of slices of 30; slice thickness of 6 mm; bandwidth of 2548 Hz/Px. The data were split into training and testing sets (Table 1). Additionally, a reference-free ghost correction algorithm Skare et al. (38 ) was implemented to remove the N/2 ghosting artifact. The acquisition time was about 12 s for each b value.
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2

MRI Scan of Filipino Participants

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Twenty-six participants were scanned at the University of Lübeck (Lübeck, Germany). (Bruggemann et al., 2016 (link); Hanssen et al., 2018 (link)) All participants were ethnic Filipinos. The mean age of this cohort was 35.7 years (range: 19–53). Twenty-five participants were right-handed, and one was ambidextrous. Seven participants were female; 19 were male. Twenty-three were scanned on a Philips Achieva MRI; 3 were scanned on a Philips Ingenia MRI.
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3

Multi-Modal Brain Imaging Protocol

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Brain imaging was performed with a 3.0T Philips Ingenia MRI (Philips, Best, The Netherlands) equipped with an 8-channel head coil. Three structural imaging sequences were included: 1) T1-weighted anatomical images using a 3-dimensional gradient echo sequence with a field of view, FOV, 250 × 250 mm, matrix 227 × 227, slice thickness 1.2 mm, slice gap 0.6 mm, number of slices 301, echo time, TE, 3.58ms, repetition time, TR 7.69ms). 2) T2-FLAIR (fluid-attenuated inversion recovery); FOV 230 × 230 mm, matrix 234 × 234, slice thickness 4 mm, slice gap 0.4 mm, number of slices 37, TE = 125 ms; TR = 11000 ms, inversion time, TI, 2800 ms for suppression of water signal for better lesion detection. 3) T2-weighted FFE (fast field echo) images; FOV 230 × 183 mm, matrix 256 × 205, slice thickness 4 mm, slice gap 1 mm, number of slices 30, TE 16 ms, TR 500 ms. The BOLD resting-state functional MRI protocol consisted of a gradient echo-planar sequence with FOV 230 × 230 mm, matrix 96 × 96, slice thickness 4 mm, TE = 35 ms, TR = 3000 ms, flip angle = 90°, and voxel size of 2.4 × 2.4x4 mm. The acquisition time was 8 min and the total number of volumes acquired were 160. Patients were instructed to keep their eyes closed, to think about nothing in particular and not to fall asleep.
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4

MRI Scan of Filipino Participants

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Twenty-six participants were scanned at the University of Lübeck (Lübeck, Germany). (Bruggemann et al., 2016 (link); Hanssen et al., 2018 (link)) All participants were ethnic Filipinos. The mean age of this cohort was 35.7 years (range: 19–53). Twenty-five participants were right-handed, and one was ambidextrous. Seven participants were female; 19 were male. Twenty-three were scanned on a Philips Achieva MRI; 3 were scanned on a Philips Ingenia MRI.
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5

Standardized 3T MRI Acquisition Protocol

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The MRI protocol has previously been described [14 (link), 15 (link)], and followed a standardized protocol. MRI acquisitions were obtained using a 3T Philips Ingenia MRI scanner (Philips Medical systems, Best, The Netherlands).
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6

Relaxivity Measurements of Fe-PyC3A Complexes

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In vitro testing involving measuring changes of relaxation times at 3T (3T Philips Ingenia MRI) were performed at room temperature (21oC). The stock solution of Fe-PyC3A was diluted in degassed and nitrogen-saturated DPBS, pH 6.5, containing 5 mM glucose, stored under argon, and used within 1 h. The stock solution of Fe2+-PyC3A was serially diluted (0–5 mM) with DPBS in the absence or in the presence of 5 mM sodium ascorbate. In some experiments DPBS was replaced by fresh rabbit blood plasma for diluting Fe2+-PyC3A stock solution. The solutions lacking ascorbate were incubated for 1 h in the presence of either 1.5U/ml glucose oxidase (GOX, recombinant from Aspergillus niger, Calbiochem) or 3U/ml MPO (1600 U/ml, Meridian Bio Sciences) combined with 1.5 U/ml GOX. To determine relaxivity of completely oxidized Fe3+-PyC3A we used 0–5 mM solutions of independently isolated Fe3+-PyC3A as well as 0–5 mM Fe2+-PyC3A solutions oxidized in the presence of 5 mM H2O2 (Sigma-Aldrich) for 1 h before MRI. Mean T1 and T2 values were obtained by ROI analysis of T1 and T2 maps derived from MR images of agarose-immersed phantoms. Data were plotted as 1/T1,2 vs Fe-PyC3A concentration to calculate r1,2 of Fe. Fe concentrations were determined by ICP-AES or spectrophotometry of H2O2 - oxidized Fe samples (ferric thiocyanate, (17 )).
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7

3T MRI Structural Imaging Protocol

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All image data were obtained with the same 3 Tesla Philips Ingenia MRI scanner (Philips Medical Systems) with equal imaging protocol settings at all time points: 3D T1-weighted image (T1 magnetization-prepared rapid gradient-echo [MPRAGE]) in sagittal plane; time to inversion: 853 ms; repetition time: “shortest” (typically 5.1 ms); echo time: “shortest” (typically 2.3 ms); flip angle: 8 degrees; field of view: 256 × 256 cm; and matrix: 256 × 256 pixels (reconstructed to 512 × 512 pixels). We sampled 184 overlapping 1 mm isotropic voxels, which were automatically reconstructed to 368 slices with 0.5 mm thickness. Acquisition time was 6 minutes and 29 seconds.
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8

High-Resolution T2-Weighted Brain Imaging

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Scans were acquired on an Ingenia 3.0-T system (Philips Healthcare, Best, The Netherlands) combined with a commercially available small animal coil (Philips Research, Hamburg, Germany) with heating function to preserve body temperature during the examination. The protocol consisted of one axial multi-shot T2-weighted turbo-spin-echo (TSE) sequence with the following parameters: echo time 65 ms, repetition time 1,540 ms, flip angle 90°, field of view 40 × 40 mm, matrix 256 × 256, slice thickness 1 mm without gap, acquired voxel size 0.19 × 0.27 × 1 mm, and reconstructed voxel size 0.15 × 0.15 × 1 mm, number of signal acquisitions 6. Standard scan time for 15 slices was 5:05 min. The detailed scan protocol of the T2-weighted sequence is available at the supplement for all vendors, as well as an ExamCard for Philips 3.0T Achieva and Ingenia MRI systems ready to use.
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9

Resting-State fMRI Acquisition Protocol

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All participants were scanned using a 3.0-T Ingenia MRI scanner (Philips Healthcare, The Netherlands) at the Department of Medical Imaging of Guangdong No. 2 Provincial People’s Hospital. During R-fMRI data acquisition, participants were asked to lie quietly with their eyes closed and not think of anything specific or fall asleep while inside the scanner. The detailed acquisition parameters were as follows: repetition time (TR) = 2,000 ms, echo time (TE) = 35 ms, flip angle (FA) = 90°, slice thickness = 3.6 mm with a 0.7-mm gap, matrix = 64 × 64, field of view (FOV) = 230 mm × 230 mm, and 35 transverse planes parallel to the AC–PC line. The R-fMRI scan lasted for 8 min, and a total of 240 volumes were obtained for each participant. In addition, individual high-resolution anatomical images were acquired using a T1-weighted three-dimensional volumetric magnetization-prepared rapid acquisition gradient-echo sequence: 185 axial slices, TR = 8.4 ms, TE = 3.9 ms, FA = 8°, slice thickness = 1.0 mm, no gap, matrix = 256 × 256, and FOV = 256 mm × 256 mm.
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10

Diffusion MRI of Neurological Integrity

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Participants underwent diffusion magnetic resonance imaging at the Keller Center for Imaging Innovation at Barrow Neurological Institute, Phoenix, Arizona. A 3-Tesla Philips Ingenia MRI (Philips, Healthcare) was used to acquire data using single-shell diffusion weighted acquisitions with the following parameters: 32 diffusion-encoding directions (b-value: 2500 s/mm2. TR/TE: 7065/119 ms; flip-angle = 90°; matrix: 92 × 90; voxel size: 3.0 mm × 3.0 mm; slice thickness: 3.0 mm; number of averages = 1) and one B0 image at the beginning of the acquisition. All MR images were screened for neuropathology by a licensed neuroradiologist prior analysis.
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