Demographic data such as age, sex, body mass index, smoking status quantified in packs per year (P/A), inhaled treatment prescribed before exacerbation, as well as the use and duration of oral steroids during the exacerbation were collected. The total serum IgE concentration (immunoassay technique, ImmunoCAP IgE total, Thermo Fisher Scientific, Phadia AB, Uppsala, Sweden), blood eosinophilia (Beckman Coulter LH 780 Controlled Analyzer), and C-reactive protein (Beckman Coulter LH 780 Controlled Analyzer, Holliston, Mass) were also collected. The severity of exacerbations was characterized by the length of the hospital stay including the time spent in the emergency room and if the patient needed to be treated in the intensive care unit. Controlled asthma was defined as an asthma control test score greater than or equal to 20 points in the month preceding the consultation.
Verduyn M., Botto G., Jaubert J., Lier C., Flament T, & Guilleminault L. (2019). Serum IgG Concentrations in Adult Patients Experiencing Virus-Induced Severe Asthma Exacerbations. The Journal of Allergy and Clinical Immunology. in Practice, 7(5), 1507-1513.e1.
+ Open protocol