D2O), DCl (20% concentration solution in D2O),
and NaOD (30% concentration solution in D2O) were purchased
from Goss Scientific (U.K.). Neamine free-base was purchased from
Carbosynth (U.K.). 2-Deoxystreptamine dihydrobromide, neomycin sulfate,
paromomycin sulfate, streptomycin potassium hydrogen phthalate, disodium
tetraborate, sodium trimethylsilylpropanoate (TMSP), and nitromethane
(CH3NO2) were purchased from Sigma–Aldrich
(U.K.).