3t verio system

MRI investigations were performed on a 3T Verio system (Siemens Healthineers, Erlangen, Germany) installed in the research setting of the Edinburgh Imaging facility at The Queen’s Medical Research Institute (QMRI), University of Edinburgh, in a manner consistent with the recommendations of the Safety Committee of the International Society of Magnetic Resonance in Medicine (ISMRM) (Calamante et al., 2015 (link)). On each occasion, contiguous series of T2-weighted (T2W) MRI images were acquired in the sagittal plane using a fast spin echo (FSE) pulse sequence with the following acquisition parameters, repetition time (TR): 3950 ms, echo time (TE): 100 ms, flip angle: 150°, slice thickness: 5 mm, spacing between slices: 5 mm, field of view (FOV): 199 × 199 mm, matrix size: 384 × 288, and one average. The FSE T2W MR images were reviewed together with standard diagnostic series of MR images by a radiologist who also noted whether there were imaging signs to indicate the presence of adenomyosis.

Six volunteers (3 female, mean age 31 ± 9 years) were recruited and scanned under a technical‐development protocol, under agreement with local ethics and institutional committees, on a 3T Verio system (Siemens Healthcare, Erlangen, Germany) with a 32‐channel receive‐only head coil. All scanning occurred during a single scan session for each volunteer. The volunteers were asked to lie still during the scan but were not required to stay awake.
The ASL data were acquired using a 2D‐SPGR radial readout, similar to that used in Berry et al,²⁵ to facilitate rapid scans so that all of the protocols could be acquired within a single session. A three‐plane localizer was used to place the 70‐mm‐thick, transverse, ASL imaging slab approximately centered at the inferior edge of the thalamus with the superior edge including the corpus callosum (Figure 1B). A single‐slab 3D time‐of‐flight sequence (0.31 × 0.31 × 1.3 mm³) was used to place the transverse PCASL labeling plane at the middle of the V3 section of the vertebral arteries.

All data were acquired using a 3T Verio system (Siemens AG, Healthcare Sector, Erlangen, Germany). Standard cardiac imaging planes and a short axis stack of left ventricular cine data were acquired using routine steady state free precession (TrueFISP) acquisitions. Native T₁ relaxation rates (i.e. in the absence of CA) were calculated using the modified Look-Locker inversion (MOLLI) recovery technique [13 (link)]. Stress imaging was performed by intravenous infusion of 140 μg/kg/min of adenosine (Adenoscan, Sanofi Aventis). Fifty dynamic perfusion images were obtained at diastole across three short-axis view slices: basal, mid-ventricular and apical slices according to the standard 16-segment heart model [14 (link)]. Perfusion images were acquired using a turbo-fast low angle shot (FLASH) saturation recovery prepared single-shot gradient echo pulse sequence (repetition time/ echo time 2.20 ms/1.07 ms, flip angle 12^o, slice thickness 8 mm, preparation pulse delay (PD) to central line of k-space 100 ms, matrix size 192 × 108 and FoV 330 mm × 440 mm). With the application of GRAPPA (accelerator factor of 3) and partial Fourier acquisition of 0.75, each dynamic frame consisted of 48-phase encoded lines. All CMR perfusion data were acquired using electrocardiogram-gating.

The MR scan was performed on a 3T Verio system (Siemens AG, Erlangen, Germany) using a 15-channel Tx/Rx knee coil. A 3D-FLASH sequence (with TE = 3.2 ms, TR = 620 ms, 128 × 128 × 80 matrix, 0.78 × 0.78 × 1.1 mm³ resolution, 32 repetitions) acquired the image in 25 min. Chemical shift artefacts occur in the frequency-encoded direction from left to right.