Gemini tf ct scanner

Manufactured by Philips

The Gemini TF CT scanner is a medical imaging device manufactured by Philips. It is designed to capture high-quality computed tomography (CT) scans of the human body. The Gemini TF CT scanner utilizes advanced imaging technology to provide detailed, three-dimensional images of internal structures for diagnostic and clinical purposes.

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Gemini Astonish TF 16 PET/CT scanner Gemini TF Big Bore PET/CT scanner Gemini TF-64 PET/CT scanner Gemini TF 16 PET/CT scanner Gemini TF PET/CT scanner Gemini TF scanner Gemini TF CT scanners

2 protocols using gemini tf ct scanner

FDG-PET Diagnostic Protocol for Disorders of Consciousness

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The FDG‐PET (Gemini TF CT scanner, Philips Medical Systems) was performed approximately 30 minutes after intravenous injection of 5–10 mCi (185–370 MBq) FDG in a resting state, awake, eyes open condition in a dark and quiet room.
The FDG‐PET standardised uptake value (SUV) was calculated to approximate the cerebral metabolic rate of glucose: SUV=Decay corrected Voxel IntensityInjected DoseBody Weight at single subject level. The brain FDG‐PET SUV of each patient with an unequivocal and reliable bedside diagnosis of VS/UWS or MCS was visually inspected by three experts in the analyses of FDG‐PET of DOC patients. They were blinded to the clinical diagnosis and they categorized each patient as VS/UWS or MCS based on the SUV level in the fronto‐parietal network. Discrepancies were discussed to reach a common consensus FDG‐PET diagnosis for all patients. The degree of agreement between the three experts was calculated using the Cohen's kappa (K). Clinical VS/UWS patients were subsequently classified as MCS*¹³ if they were categorized as MCS based on the SUV.²² The study cohort was thus divided into three groups: (1) VS/UWS patients (clinical diagnosis and FDG‐PET diagnosis of VS/UWS); (2) MCS* patients (clinical diagnosis of VS/UWS but FDG‐PET diagnosis of MCS), and (3) MCS patients (clinical and FDG‐PET diagnosis of MCS) (Fig 2).

Thibaut A., Panda R., Annen J., Sanz L.R., Naccache L., Martial C., Chatelle C., Aubinet C., Bonin E.A., Barra A., Briand M., Cecconi B., Wannez S., Stender J., Laureys S, & Gosseries O. (2021). Preservation of Brain Activity in Unresponsive Patients Identifies MCS Star. Annals of Neurology, 90(1), 89-100.

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FDG-PET Imaging of Cerebral Glucose Metabolism

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We acquired FDG-PET data with a Gemini TF CT scanner (Philips Medical Systems). Following intravenous injection of 150 to 300 MBq FDG, we recorded a single PET frame for 12 minutes, after circulation of the tracer for at least 30 minutes. We kept the patients awake during the uptake period. The images were corrected for attenuation using X-ray computed tomography, as well as for random scatter and physical decay. All data were preprocessed as described elsewhere, 15 smoothed with an isotropic 14 mm full-width at half-maximum (FWHM) Gaussian kernel and analyzed using Statistical Parametric Mapping 12 (SPM12; Wellcome Department of Cognitive Neurology, London, UK). To partially overcome the issue of brain lesions, the normalization was performed using a customized FDG template as described in a previous study. 16 A global normalization was performed by proportional scaling. We used the FDG-PET standardized uptake values (SUV) to estimate the global cerebral metabolic rate of glucose consumption:

Aubinet C., Cassol H., Gosseries O., Bahri M.A., Larroque S.K., Majerus S., Martial C., Martens G., Carrière M., Chatelle C., Laureys S, & Thibaut A. (2020). Brain Metabolism but Not Gray Matter Volume Underlies the Presence of Language Function in the Minimally Conscious State (MCS): MCS+ Versus MCS- Neuroimaging Differences. Neurorehabilitation and neural repair, 34(2).

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