Hydrophobic SPIO nanoparticles were synthesized by our laboratory and stored in hexane according to a previously reported method.31 (link) DSPE-PEG5k was purchased from Avanti Polar Lipids, Inc. (Alabaster, AL, USA). The NIR dye Cy5-N-hydroxysuccinimide (Cy5-NHS) was obtained from Xi’an Ruixi Biological Technology Co., Ltd. (Xi’an, Shaanxi, China). The peptide Bom with a sequence of {Lys(N3)}QRLGNQWAVGHLM was synthesized by GenScript Biotech Corp. (Piscataway, NJ, USA). Cell Counting Kit-8 (CCK-8) was purchased from Dojindo Molecular Technologies, Inc. (Shanghai, China). All reagents were of analytical grade and were used as received.
Dspe peg5k
Manufactured by Avanti Polar Lipids
Sourced in United States
DSPE-PEG5k is a pegylated phospholipid produced by Avanti Polar Lipids. It consists of a distearoylphosphatidylethanolamine (DSPE) head group covalently linked to a polyethylene glycol (PEG) chain with an average molecular weight of 5,000 Da. This product is commonly used in liposome and nanoparticle formulations to improve their pharmacokinetic properties and biodistribution.
Automatically generated - may contain errors
Lab products found in correlation
Cell counting kit 8 cck 8, by Dojindo Laboratories (1 mentions)
Pd 10 desalting column, by GE Healthcare (1 mentions)
Chlorpromazine, by Cayman Chemical (1 mentions)
Cytochalasin d, by Cayman Chemical (1 mentions)
Hoechst 3342, by Thermo Fisher Scientific (1 mentions)
Lysotracker red dnd 99, by Thermo Fisher Scientific (1 mentions)
Soybean lecithin s100, by Lipoid (1 mentions)
Dynasore, by MedChemExpress (1 mentions)
Sucrose, by Merck Group (1 mentions)
3 protocols using dspe peg5k
1
Synthesis and Characterization of SPIO Nanoparticles
2
DSPE-PEG-LyP-1 Conjugation Protocol
3
Formulation and Characterization of DTX Nanoparticles
Check if the same lab product or an alternative is used in the 5 most similar protocols
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DTX was supplied by Qilu Pharmaceutical (Jinan, China). DSPE-PEG2K was purchased from NOF (Tokyo, Japan). DSPE-PEG5K was obtained from Avanti Polar Lipids. (Alabaster, AL). 3,3′-Dioctadecyloxacarbocyanine perchlorate (DIO), nystatin, and sucrose were obtained from Sigma-Aldrich (St. Louis, MO). 1,1’-Dioctadecyltetramethyl indotricarbocyanine iodide) (DIR) was purchased from Perkin-Elmer (Waltham, MA). Soybean lecithin (Lipoid S-100) was obtained from Lipoid GmbH (Ludwigshafen, Germany). Chlorpromazine and cytochalasin D were supplied by Cayman Chemicals (Ann Arbor, MI). Dynasore was obtained from MedChem Express (Monmouth Junction, NJ). LysoTracker Red DND-99 and Hoechst3342 were obtained from Thermo Fisher Scientific (Waltham, MA). The anti-PEG backbone mAb AGP4 was provided by Dr. Steve R. Roffler (Academia Sinica, Taipei, Taiwan). Tynen® (solvent-based DTX) is a generic product of DTX manufactured by TYY Pharmaceutical (lot no: STW1407, Taipei, Taiwan). All reagents were of analytical grade and solvents used in the high-performance liquid chromatography (HPLC) or ultra-performance liquid chromatography (UPLC)/mass spectrometry (MS/MS) analysis was of HPLC or MS grade.
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