Patients presenting to the vitiligo clinic were asked for full history of their disease and the Vitiligo Area Scoring Index (VASI) was calculated as described in the literature (Σ all body sites (hand units) x depigmentation).17 (link)
All study subjects underwent a full ophthalmological examination including corrected distance visual acuity (CDVA) measurement using a Snellen chart, slit-lamp biomicroscopy, intraocular pressure (IOP) measurement using Goldmann Applanation Tonometry, cycloplegic refraction, and fundus examination.
Patients were then examined using spectral domain-OCT (Retinascan RS-3000 advance; NIDEK, Gamagori, Japan). Dilated eyes eligible for the study were subjected to choroidal mode imaging using line scans. Subfoveal choroidal thickness was then manually determined on static output images. Subfoveal choroidal thickness was measured as a perpendicular line extending from the hyperreflective RPE line in the foveal region to the line representing the sclero-choroidal interface. Measurements were determined by two independent investigators, and the mean measurement was obtained as the outcome. All measurements were taken during the daytime between 9 am and 12 am to avoid diurnal variation patterns of choroidal thickness.
All study subjects underwent a full ophthalmological examination including corrected distance visual acuity (CDVA) measurement using a Snellen chart, slit-lamp biomicroscopy, intraocular pressure (IOP) measurement using Goldmann Applanation Tonometry, cycloplegic refraction, and fundus examination.
Patients were then examined using spectral domain-OCT (Retinascan RS-3000 advance; NIDEK, Gamagori, Japan). Dilated eyes eligible for the study were subjected to choroidal mode imaging using line scans. Subfoveal choroidal thickness was then manually determined on static output images. Subfoveal choroidal thickness was measured as a perpendicular line extending from the hyperreflective RPE line in the foveal region to the line representing the sclero-choroidal interface. Measurements were determined by two independent investigators, and the mean measurement was obtained as the outcome. All measurements were taken during the daytime between 9 am and 12 am to avoid diurnal variation patterns of choroidal thickness.