Vinblastine was obtained from Tocris Bioscience
(Minneapolis, MN, USA); GST-hPXR-LBD, LanthaScreen Tb-anti-GST antibody,
TR-FRET PXR (SXR) assay buffer, BODIPY FL Vinblastine, and 1 M DTT
(dithiothreitol) were purchased from Invitrogen (Carlsbad, CA, USA);
human glutathione S transferase protein (GST) was purchased from Abcam
(Cambridge, MA, USA); catharanthine and vindoline were purchased from
LKT Laboratories, Inc. (St. Paul, MN, USA); deacetyl Vinblastine was
purchased from Toronto Research Chemicals, Inc. (Toronto, Ontario,
Canada); dimethyl sulfoxide (DMSO) was purchased from Fisher Scientific
(Pittsburgh, PA, USA); TO901317 was purchased from Cayman Chemical
(Ann Arbor, MI, USA); SR12813 was purchased from Enzo Life Sciences
(Farmingdale, NY, USA); clotrimazole, rifampicin, 2-amino-2-(hydroxymethyl)-1,3-propanediol
(Tris), potassium chloride (KCl), 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate
hydrate (CHAPS), and bovine serum albumin (BSA) were purchased from
Sigma (St. Louis, MO, USA); hyperforin, ginkgolide A, and ginkgolide
B were purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA);
and black 384-well polypropylene plates were purchased from Matrical
Bioscience (Spokane, WA, USA).
(Minneapolis, MN, USA); GST-hPXR-LBD, LanthaScreen Tb-anti-GST antibody,
TR-FRET PXR (SXR) assay buffer, BODIPY FL Vinblastine, and 1 M DTT
(dithiothreitol) were purchased from Invitrogen (Carlsbad, CA, USA);
human glutathione S transferase protein (GST) was purchased from Abcam
(Cambridge, MA, USA); catharanthine and vindoline were purchased from
LKT Laboratories, Inc. (St. Paul, MN, USA); deacetyl Vinblastine was
purchased from Toronto Research Chemicals, Inc. (Toronto, Ontario,
Canada); dimethyl sulfoxide (DMSO) was purchased from Fisher Scientific
(Pittsburgh, PA, USA); TO901317 was purchased from Cayman Chemical
(Ann Arbor, MI, USA); SR12813 was purchased from Enzo Life Sciences
(Farmingdale, NY, USA); clotrimazole, rifampicin, 2-amino-2-(hydroxymethyl)-1,3-propanediol
(Tris), potassium chloride (KCl), 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate
hydrate (CHAPS), and bovine serum albumin (BSA) were purchased from
Sigma (St. Louis, MO, USA); hyperforin, ginkgolide A, and ginkgolide
B were purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA);
and black 384-well polypropylene plates were purchased from Matrical
Bioscience (Spokane, WA, USA).