Dronedarone

Manufactured by Selleck Chemicals

Sourced in China

Dronedarone is a laboratory device used for the preparation and analysis of chemical compounds. It is designed to efficiently handle and process small quantities of materials, enabling researchers to conduct experiments and tests with precision and consistency.

Automatically generated - may contain errors

Lab products found in correlation

Fetal bovine serum (fbs), by Thermo Fisher Scientific (3 mentions) Dulbecco s modified eagle medium, by Thermo Fisher Scientific (2 mentions) H9c2 cells, by Selleck Chemicals (1 mentions) Ang 2, by Selleck Chemicals (1 mentions) H9c2 cell, by American Type Culture Collection (1 mentions) Sotalol, by Selleck Chemicals (1 mentions) Dimethyl sulfoxide (dmso), by Thermo Fisher Scientific (1 mentions) Amiodarone, by Selleck Chemicals (1 mentions) Rpmi medium, by Thermo Fisher Scientific (1 mentions) Ovcar 3 cells, by American Type Culture Collection (1 mentions) Penicillin streptomycin p s, by Thermo Fisher Scientific (1 mentions) Phosphate buffered saline (pbs), by Corning (1 mentions)

2 protocols using dronedarone

Ang II-induced H9C2 cell model of MH

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H9C2 cells were bought from ATCC (Rockville, MD, USA). All cells were maintained in Dulbecco’s Modified Eagle medium (Thermo Fisher Scientific, Waltham, MA, USA) with 10% fetal bovine serum (Thermo Fisher Scientific) and 1% antibiotics (Beyotime, Shanghai, China) under the condition of 5% CO₂ and 37°C.
H9C2 cells were treated with 50, 100, 150 nmol/L Ang II (BIOFOUNT, Beijing, China) for 48 hours to establish a cell model of MH.
In addition, different concentrations of dronedarone (1, 5, 10 μM) (Selleck, Shanghai, China) were used to treat Ang II-induced H9C2 cells for 6 hours.

Chen C., Hu S., Hu H.J., Liu Z.X., Wu X.T., Zou T, & Su H. (2024). Dronedarone Attenuates Ang II-Induced Myocardial Hypertrophy Through Regulating SIRT1/FOXO3/PKIA Axis. Korean Circulation Journal, 54(4), 172-186.

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Ovarian Cancer Cell Culture Protocol

Cited 1 time

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Cells were cultured in 10 cm plates in a humidified atmosphere (5% CO₂) at 37 °C. At 70–90% confluence, trypsin (0.25%)/EDTA solution (Corning) was used to detach the cells from the culture plate for passaging and used for further experiments until passage 20. OV81.2 and OV81.2-CP10 primary cell line models were generated as previously described [10 (link)]. A2780 and CP70 cells were obtained from Dr. Paul Modrich (Duke University). OVCAR3 cells were purchased from ATCC. OV81.2, OV81.2-CP10, A2780, CP70, ALDH^high CP70, ALDH^low CP70, OVCAR8 and 293 T cells were cultured in DMEM medium supplemented with 10% FBS (Gibco) and 1% penicillin-streptomycin (PS) (Gibco). OVCAR3 and OVCAR3-CP38 cells were cultured in RPMI medium (Gibco) with 10% FBS and 1%PS. Phosphate-buffered saline (PBS) was purchased from Corning. Amiodarone, dronedarone, ibutilide and sotalol were purchased from SelleckChem. Dimethyl sulfoxide (DMSO) was purchased from Fisher Chemical.

Nagaraj A.B., Joseph P., Kovalenko O., Wang Q., Xu R, & DiFeo A. (2018). Evaluating class III antiarrhythmic agents as novel MYC targeting drugs in ovarian cancer. Gynecologic oncology, 151(3), 525-532.

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