Accu chek glucometers and test strips

Manufactured by Roche

Accu-chek glucometers and test strips are devices used for measuring blood glucose levels. The glucometers provide a digital readout of the glucose concentration, while the test strips are used to collect and analyze a small blood sample. These products are designed to help individuals monitor and manage their blood sugar levels.

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Accu-Chek (690 citations) Glucometer (255 citations) Accu-Chek glucometer (116 citations) Accu-Chek glucometers and strips (2 citations) Glucometer strips (2 citations)

4 protocols using accu chek glucometers and test strips

Intraperitoneal Glucose Tolerance Test

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Five-weeks after surgery, 6-hrs fasted rats were injected with 2g/kg 25% dextrose (Phoenix Pharmaceutical, St. Joseph, MO) intraperitoneally (IP). Blood glucose was measured at baseline (0), 15, 30, 45, 60 and 120-min using Accu-chek glucometers and test strips (Roche, Indianapolis, IN). All blood samples were obtained from the tip of the tail vein of freely moving rats.

Alvarez R., Lewis A.G., Toure M.H, & Seeley R.J. (2018). A Comparison of Rodent Models of Vertical Sleeve Gastrectomy. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 14(10), 1471-1479.

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Glucose Tolerance Test with Enzyme Inhibitors

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Rats fed with chow diet were fasted for 16 h and infused i3vt with saline, GFAT inhibitor (150 μg) or GNPDA2 inhibitor (150 μg) 1 h prior to starting a GTT. Intraperitoneal glucose (1.5 mg/g of body weight) was injected and blood glucose levels were measured at 0, 15, 30, 45, 60, and 120 min after glucose administration in duplicate samples using Accu-chek glucometers and test strips (Roche, Indianapolis, IN). Blood was collected from the tail vein at indicated time points for measurement of plasma insulin (ELISA, Crystal Chem, Downers Grove, IL).

Gutierrez-Aguilar R., Grayson B.E., Kim D.H., Yalamanchili S., Calcagno M.L., Woods S.C, & Seeley R.J. (2021). CNS GNPDA2 Does Not Control Appetite, but Regulates Glucose Homeostasis. Frontiers in Nutrition, 8, 787470.

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Intraperitoneal Glucose Tolerance Test

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GTT was performed at 5 wk. Rats were fasted for 8 h. After a baseline blood sample was taken (0 min), 50% D-glucose (Phoenix Pharmaceutical, St. Joseph, MO) was injected ip or gavaged. Blood glucose was measured at baseline (0), 15, 30, 45, 60 and 120 min after glucose administration on duplicate samples using Accu-chek glucometers and test strips (Roche, Indianapolis, IN). All blood samples were obtained from the tip of the tail vein of freely moving rats. Each rat received a dose of glucose equal to 1.25 g/kg body weight for the ip GTT. Rats were excluded from the data analysis if they did not exhibit a rise in blood glucose of greater than 20 mg/dL in the first 15 min after injection or if they exhibited diarrhea, as this indicates that the glucose injection did not enter the ip cavity. Plasma insulin was measured at 0 and 15 min.

Ressler I.B., Grayson B.E, & Seeley R.J. (2014). Metabolic, Behavioral and Reproductive Effects of Vertical Sleeve Gastrectomy in an Obese Rat Model of Polycystic Ovary Syndrome. Obesity surgery, 24(6), 866-876.

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Glucose Tolerance Testing in Metabolic Surgery Rats

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Five weeks after metabolic surgery, rats in cohorts 1 and 2 underwent an intraperitoneal glucose tolerance test (IPGTT) by injecting 2g/kg 25% dextrose (Phoenix Pharmaceutical, St. Joseph, MO) intraperitoneally after a 5-hr fast. Blood glucose levels were measured at baseline, 15, 30, 45, 60 and 120-min using Accu-chek glucometers and test strips (Roche, Indianapolis, IN). Insulin levels at baseline were also sampled for animals in cohort 2. Baseline glucose and insulin values were used to calculate the homeostatic model assessment for insulin resistance (HOMA-IR). All blood samples were obtained from the tip of the tail vein of moving rats.
Seven weeks after metabolic surgery, animals in cohort 3 underwent an intravenous glucose tolerance test (IVGTT) as described elsewhere, ^{9 (link)} by injecting 1g/kg of 25% dextrose (Phoenix Pharmaceutical, St. Joseph, MO) into the cannulated IJV after a 5-hr fast. Blood samples for insulin and glucose levels were then obtained from the cannulated carotid artery at 10 minutes prior to dextrose injection and 1, 2, 12, 16, 20, 30, 45, and 60 minutes following injection.

Alvarez R., Sandoval D.A, & Seeley R.J. (2019). A Rodent Model of Partial Intestinal Diversion: A Novel Metabolic Operation. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 16(2), 270-281.

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