Icap 6500 duo icp aes

The phosphorus acid DOTA analogues, DO3AP PrA , DO3AP and DO3AP ABn ( prepared as hydrates according to elemental analysis) were synthesized according to the literature. 37, 44, 45 DOTA (reagent grade) was obtained from Macrocyclics. Analytical grade (conc. aq. HCl, conc. aq. ammonia, MeOH, EtOH, HNO 3 , ammonium acetate) or pure reagent grade (all other chemicals) reagents were obtained commercially and were used as received unless otherwise specified. Deionized water (18.2 MΩ cm -1 ; Milli-Q, Millipore) was used throughout the work. Solid-phase extraction resin based on DGA (N,N,N′,N′tetra(n-octyl)diglycolamide;
Triskem), cation AG1-X8 (200-400 mesh, Cl --form; Bio-Rad), anion AG50W-X8 (200-400 mesh, H + -form; Sigma) exchangers, and Chelex-100 (imino-diacetate functionalized resin; Sigma) were purchased. The concentrations of stable scandium together with potential metals present in the solutions were analysed by ICP-AES (ThermoFischer ICAP 6500 DUO ICP-AES). The wavelengths for each element were selected in order to give the best relative emissions and to prevent interferences. To calibrate the ICP-AES, commercially available single-and multi-element standards (∼10 ppm, SCP Science) were used in dilute nitric acid (1% w/w). The acidic solutions of the radioisotope batches were collected and were diluted in aq. HNO 3 (1% w/w) prior to the analysis.