LPS (Escherichia coli 055:B5) (L2880), fluoxetine (PHR1394) and the anti-β-actin antibody (A3854) conjugated to HRP was purchased from Sigma (St. Louis, USA). Corticosterone (C0388) was purchased from TCI (Tokyo, Japan). K252a was purchased from Alomone (Jerusalem, Israel). U0126 (sc-222395) was purchased from Santa Cruz (Santa Cruz, USA). The miR-34a-5p mimic (miR10000542-1), miR-34a-5p mimic control (miR1N0000002-1), miR-34a-5p agomir (miR40000542-4), agomir control (miR4N0000002-4), miR-34a-5p antagomir (miR30000542-4) and antagomir control (miR3N0000002-4) were purchased from Ribobio Co., Ltd. (Guangzhou, China). The dual-luciferase reporter assay kit (E1910) was purchased from Promega (Madison, USA). The primary antibody against pTrkB (CY5598) was purchased from Abways (Shanghai, China). The primary antibodies against TrkB (4603), pMEK1 (9127), MEK1 (2352), pERK (4370) and ERK (4695) were purchased from Cell Signaling (Cambridge, USA). The primary antibodies against Bcl-2 (ab692) and synaptotagmin-1 (ab13259) was purchased from Abcam (Cambridge, USA).
U0126 sc 222395
Manufactured by Santa Cruz Biotechnology
Sourced in United States
U0126 (sc-222395) is a chemical compound that functions as a specific inhibitor of the mitogen-activated protein kinase (MAPK) kinases MEK1 and MEK2. It is commonly used as a research tool to study the role of the MAPK/ERK signaling pathway in various cellular processes.
Automatically generated - may contain errors
Lab products found in correlation
2 protocols using u0126 sc 222395
1
Neuroimmune Modulation of Depression
2
Neuroprotective Agents in Intracerebral Hemorrhage
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Human serum albumin (25% solution, Baxter Healthcare Corp) was administered via the IV route at 1 h after ICH induction as previously reported [19 (link)]. U0126 (sc-222395, Santa Cruz Biotechnology, USA) [31 (link)] and ML385 (30 mg/kg) (6887, Tocris, USA) [32 (link)] diluted in 5% dimethyl sulfoxide (DMSO) were intraperitoneally administered 1 h before ICH induction.
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