Dspe peg3400 maleimide

Manufactured by Laysan Bio

Sourced in United States

DSPE-PEG3400-maleimide is a water-soluble, heterobifunctional linker molecule composed of distearoylphosphatidylethanolamine (DSPE) and polyethylene glycol (PEG3400) with a maleimide functional group. It is commonly used in the development of various bioconjugates and drug delivery systems.

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Lab products found in correlation

1 2 distearoyl sn glycero 3 phosphoethanolamine n methoxy polyethylene glycol 2000 dspe peg2000, by Avanti Polar Lipids (2 mentions) 1 2 dioleoyl sn glycerol 3 phosphocholine dopc, by Avanti Polar Lipids (2 mentions) 1 1 dioctadecyl 3 3 3 3 tetramethylindodicarbocyanine 4 chlorobenzenesulfonate salt did, by Biotium (1 mentions) 1 1 dioctadecyl 3 3 3 3 tetramethylindotricarbocyanine iodide dir, by Biotium (1 mentions) Cholesterol, by Merck Group (1 mentions)

2 protocols using dspe peg3400 maleimide

Lipid Nanoparticle Formulation Protocol

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1.2-Dioleoyl-sn-glycerol-3-phosphocholine (DOPC), and 1.2-distearoyl-sn-glycero-3- phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (DSPE-PEG₂₀₀₀) were purchased from Avanti Polar Lipids, Alabaster, AL; DSPE-PEG₃₄₀₀-maleimide was purchased from Laysan Bio Inc., Arab, AL; 1.1′-dioctadecyl-3,3,3′,3′- tetramethylindodicarbocyanine, 4-chlorobenzenesulfonate salt (DiD) was purchased from Biotium Inc., Hayward, CA; cholesterol was purchased from Millipore Sigma, Burlington, MA.

Hung J., Awasthi R., Klibanov A.L, & Kelly K.A. (2021). Identification of Novel Ligands for Targeted Antifibrotic Therapy of Chronic Pancreatitis. International Journal of Nanomedicine, 16, 5495-5512.

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Lipid-Peptide Nanoparticle Synthesis

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1,2-Dioleoyl-sn-glycerol-3-phosphocholine (DOPC) and 1,2-distearoyl-sn-glycero-3- phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (DSPE-PEG2000) were purchased from Avanti polar lipids, Miami, FL, USA; DSPE-PEG3400-maleimide was purchased from Laysan Bio Inc., Arab, AL, USA; 1,1′-Dioctadecyl-3,3,3′,3′-tetramethylindotricarbocyanine iodide (DiR) was purchased from Biotium Inc., Hayward, CA, USA; cholesterol was purchased from Millipore Sigma, Burlington, MA, USA. Peptides were synthesized by the Tufts University Peptide Synthesis Core Facility using standard FMOC chemistry and Rink-Amide resin (Tufts University, Boston, MA, USA).

Hung J., Perez S.M., Dasa S.S., Hall S.P., Heckert D.B., Murphy B.P., Crawford H.C., Kelly K.A, & Brinton L.T. (2023). A Bitter Taste Receptor as a Novel Molecular Target on Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma. Pharmaceuticals, 16(3), 389.

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