Lecithin e80

Manufactured by Lipoid

Sourced in Germany

Lecithin (E80) is a natural emulsifier and surfactant derived from soybean oil. It is composed of a mixture of phospholipids and is commonly used in various industries, such as food, cosmetics, and pharmaceuticals, to facilitate the dispersion of ingredients and improve product stability.

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Lab products found in correlation

Acetonitrile hypergrade, by Merck Group (1 mentions) Milli q ultrapure water purification system, by Merck Group (1 mentions) Glycerol, by Merck Group (1 mentions) 177lucl3, by PerkinElmer (1 mentions) Oleic acid, by Lipoid (1 mentions) Lecithin s100, by Lipoid (1 mentions) 4t1 murine breast cancer cell, by American Type Culture Collection (1 mentions) Dulbecco modified eagle medium (dmem), by American Type Culture Collection (1 mentions)

2 protocols using lecithin e80

Synthesis and Characterization of Aripiprazole and Derivatives

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Aripiprazole was obtained from Otsuka pharmaceutics (Tokyo, Japan), while N-hydroxymethyl-aripiprazole and aripiprazole lauroxil were synthesised as described below. Reagents and solvents for the synthetic work were obtained from Sigma-Aldrich (St. Louis, MO, USA) and used as received. Viscoleo, Ph. Eur Grade medium chain triglyceride, C8/C10 (MCT) was purchased from Delios V (Illertissen, Germany), lecithin (E80) for the intravenous emulsion was obtained from Lipoid AG (Ludwigshafen, Germany) and glycerol from Sigma Aldrich (St. Louis, MO, USA). Hypergrade acetonitrile from Merck (Darmstadt, Germany) was used for the HPLC–MS/MS analysis, ethanol was from De Danske Spritfabrikker (Aalborg, Denmark) and deuterated aripiprazole used as the internal standard in the bioanalysis was purchased from Toronto Research Chemicals Inc. (Toronto, ON, Canada). Purified water was obtained from a Millipore Milli-Q Ultrapure Water purification system (Billerica, MA, USA). All other chemicals were of analytical grade or higher.

Rohde M., M?rk N., Håkansson A.E., Jensen K.G., Pedersen H., Dige T., J?rgensen E.B, & Holm R. (2014). Biological conversion of aripiprazole lauroxil - An N-acyloxymethyl aripiprazole prodrug. Results in Pharma Sciences, 4, 19-25.

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Radiolabeled CPA for Cancer Treatment

Cited 1 time

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CPA was purchased from LKT Laboratories (St Paul, MN). ¹⁷⁷LuCl₃ was purchased from Perkin Elmer (Waltham, MA). Tritium-labeled CPA ([³H]CPA; 1.0 mCi/mg CPA) was obtained from Moravek Biochemicals (Brea, CA). Lecithin E80, lecithin S100, and oleic acid were purchased from Lipoid (Ludwigshafen, Germany). 1-(4-Isothiocyanatobenzyl) diethylenetriaminepentaacetic acid (DTPA-bz-SCN) was obtained from Macrocyclics (Dallas, TX). (3-(4,5-Dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium) (MTS) was purchased from Life Technologies (Carlsbad, CA). All other chemicals were purchased from Sigma-Aldrich (St. Louis, MO) or Fisher Scientific (Pittsburgh, PA).
4T1 murine breast cancer cells and Miapaca-2 human pancreatic ductal adenocarcinoma cells were purchased from American Type Culture Collection (Manassas, VA) and maintained in Dulbecco modified Eagle medium supplemented with 10% fetal bovine serum and 1% antibiotics. Both cell lines have activated Sonic Hedgehog pathway [10 (link), 23 (link), 24 (link)].

You J., Zhao J., Wen X., Wu C., Huang Q., Guan F., Wu R., Liang D, & Li C. (2015). Chemoradiation Therapy using Cyclopamine-Loaded Liquid-Lipid Nanoparticles and Lutetium-177-Labeled Core-Crosslinked Polymeric Micelles. Journal of controlled release : official journal of the Controlled Release Society, 202, 40-48.

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