Beeswax

Manufactured by Carl Roth

Sourced in Germany

Beeswax is a natural wax produced by honeybees. It is a hard, yellowish-brown solid with a characteristic beeswax aroma. Beeswax has various applications, including as a lubricant, a waterproofing agent, and a component in various products such as candles, cosmetics, and furniture polish.

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Lab products found in correlation

Polysorbate 80 tween 80, by Thermo Fisher Scientific (3 mentions) Alloxan, by Merck Group (2 mentions) Glucophage, by Merck Group (2 mentions) Coartem, by Novartis (1 mentions)

3 protocols using beeswax

Metformin-Loaded Topical Formulation

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The pure sample of metformin used was obtained as a gift from May and Baker PLC (Ikeja, Lagos State, Nigeria). Phospholipon® 90H (P90H) (Phospholipid GmbH, Köln, Germany), sorbitol (Caesar & Loretz, Hilden, Germany), sorbic acid (Foodchem Int. Co., China), polyethylene glycol 4000 (PEG 4000) (Ph. Eur. Carl Roth GmbH + Co. KG Karlsruhe, Germany), beeswax (Carl Roth, Karlsruhe, Germany), Polysorbate 80 (Tween® 80) (Acros Organics, Geel, Belgium), Capryol-PGE 860 (Gattefossé, Saint – Priest Cedex, France), Glucophage® purchased from model pharmacy University of Nigeria, Nsukka (Merck KGaA, Darmstadt, Germany), Alloxan (Merck KGaA, Darmstadt, Germany) and double distilled water (Lion water, University of Nigeria, Nsukka, Nigeria) and other solvents and reagents were used as procured from their manufacturers without further purification. Adult albino Wistar rats of both sexes were procured from the Faculty of Veterinary Medicine, University of Nigeria, Nsukka, Nigeria.

Kenechukwu F.C., Isaac G.T., Nnamani D.O., Momoh M.A, & Attama A.A. (2022). Enhanced circulation longevity and pharmacodynamics of metformin from surface-modified nanostructured lipid carriers based on solidified reverse micellar solutions. Heliyon, 8(3), e09100.

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Artemether-Lumefantrine Nanoemulsion Formulation

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Artemether was obtained from Hangzhou Dayang Chemical Co. Ltd. (Zhejiang, China), while lumefantrine was sourced from Guilin Pharmaceutical Co Ltd. (Shanghai, China). Phospholipon^® 90H (P90H) (Phospholipid GmbH, Köln,, Germany), sorbitol (Caesar &Loretz, Hilden, Germany), sorbic acid (Foodchem Int. Co., China), beeswax (Carl Roth, Karlsruhe, Germany), Polysorbate 80 (Tween^® 80) (Acros Organics, Geel, Belgium), Capryol-PGE 860 (Abitech Corp, USA), Coartem^® (Novartis, Basel, Switzerland) and distilled water (Lion water, University of Nigeria, Nsukka, Nigeria) and other solvents and reagents were used as procured from their manufacturers without further purification.
Adult albino Wistar mice of both sexes infected with Plasmodium berghei(NK 65) malaria parasites were employed in the study.

Akpa P.A., Ugwuoke J.A., Attama A.A., Ugwu C.N., Ezeibe E.N., Momoh M.A., Echezona A.C, & Kenechukwu F.C. (2020). Improved antimalarial activity of caprol-based nanostructured lipid carriers encapsulating artemether-lumefantrine for oral administration. African Health Sciences, 20(4), 1679-1697.

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Metformin-loaded Lipid Nanoparticle Formulation

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Metformin hydrochloride pure sample was obtained as a gift from May and Baker PLC (Ikeja, Lagos State, Nigeria). Phospholipon® 90H (P90H) (Phospholipid GmbH, Köln, Germany), sorbitol (Caesar & Loretz, Hilden, Germany), polyethylene glycol 4000 (PEG 4000) (Ph. Eur. Carl Roth GmbH + Co. KG Karlsruhe, Germany), beeswax (Carl Roth, Karlsruhe, Germany), Polysorbate 80 (Tween® 80) (Acros Organics, Geel, Belgium), Alloxan (Merck KGaA, Darmstadt, Germany), Glucophage® (Merck), distilled water (Lion water, University of Nigeria, Nsukka, Nigeria) and other solvents and reagents were used as procured from their manufacturers without further purification. Adult albino Wistar rats of both sexes were procured from the Faculty of Veterinary Medicine, University of Nigeria, Nsukka.

Kenechukwu F.C., Nnamani D.O., Duhu J.C., Nmesirionye B.U., Momoh M.A., Akpa P.A, & Attama A.A. (2022). Potential enhancement of metformin hydrochloride in solidified reverse micellar solution-based PEGylated lipid nanoparticles targeting therapeutic efficacy in diabetes treatment. Heliyon, 8(3), e09099.

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