Bevacizumab was obtained from F. Hoffmann-La Roche Ltd. (Basel, Switzerland). Human immunoglobulin G (HuIgG) was purchased from MP Biomedicals (Santa Ana, CA, USA). Both Bevacizumab and HuIgG were diluted with normal saline. Na-pyruvate and Geneticin™ Selective Antibiotic (G418 Sulfate) were purchased from Thermo Fisher Scientific, Inc. (Waltham, MA, USA). RPMI-1640 culture medium, d -glucose, and HEPES buffer were obtained from Sigma-Aldrich (St. Louis, MO, USA). Fetal bovine serum was obtained from Bovogen Biologicals Pty. Ltd. (Melbourne, Australia).
Human immunoglobulin g huigg
Manufactured by MP Biomedicals
Sourced in United States
Human immunoglobulin G (HuIgG) is a purified protein fraction obtained from human plasma. It is the most abundant type of antibody found in the human body, comprising approximately 75% of all serum antibodies. HuIgG plays a crucial role in the body's immune response by recognizing and neutralizing foreign substances, such as bacteria and viruses.
Automatically generated - may contain errors
Lab products found in correlation
Bevacizumab, by Roche (3 mentions)
Paclitaxel, by Fujifilm (2 mentions)
Rpmi 1640 culture medium, by Merck Group (1 mentions)
Na pyruvate, by Thermo Fisher Scientific (1 mentions)
Hepes buffer, by Merck Group (1 mentions)
Geneticin selective antibiotic g418 sulfate, by Thermo Fisher Scientific (1 mentions)
D glucose, by Merck Group (1 mentions)
Erlotinib, by Roche (1 mentions)
Pegylated liposomal doxorubicin, by Johnson & Johnson (1 mentions)
Docetaxel, by Sanofi (1 mentions)
Trastuzumab, by Roche (1 mentions)
Pertuzumab, by Roche (1 mentions)
Dm1 ch3, by LGC (1 mentions)
Capecitabine, by Roche (1 mentions)
6 protocols using human immunoglobulin g huigg
1
In Vitro Bevacizumab and Immunoglobulin Study
2
Erlotinib and Bevacizumab Drug Preparation
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Erlotinib was provided by F. Hoffmann-La Roche Ltd. (Basel, Switzerland) and was dissolved in 6% Captisol solution (ChemScene, Monmouth Junction, NJ, USA). Bevacizumab was obtained from F. Hoffmann-La Roche Ltd. Human immunoglobulin G (HuIgG) was purchased from MP Biomedicals (Santa Ana, CA, USA). Both Bevacizumab and HuIgG were diluted with saline.
3
Combination Therapy Dosage Protocols
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Bevacizumab was manufactured by Chugai Pharmaceutical Co., Ltd. (Tokyo, Japan) as a solution and diluted to 5 mg/kg body weight (0.2 ml/mouse) with saline. Human immunoglobulin G (HuIgG) was purchased from MP Biomedicals, LLC (Santa Ana, CA, USA), and was reconstituted with water and diluted to 5 mg/kg body weight (0.2 ml/mouse) with saline (Otsuka Pharmaceutical Co., Ltd., Tokyo, Japan). Paclitaxel was purchased from Wako Pure Chemical Industries, Ltd. (Osaka, Japan) and was reconstituted with 50% ethanol-50% Cremophor EL, and immediately prior to administration was diluted 10-fold with saline. PEGylated liposomal doxorubicin was purchased from Janssen Pharmaceutical, Inc. (Beerse, Belgium) as a solution and diluted to 20 mg/kg body weight (10 ml/kg body weight) with saline.
4
Preparation of Therapeutic Antibodies and Cytotoxic Agents
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Trastuzumab and pertuzumab were provided by F. Hoffmann-La Roche (Basel, Switzerland) as a fine powder and a liquid, respectively. Trastuzumab was dissolved in distilled water. The two antibodies were then diluted with saline for the in vivo experiments and culture medium for the in vitro experiments. Human immunoglobulin G (HuIgG) was purchased from MP Biomedicals, LLC (Solon, OH, USA) and was reconstituted with distilled water and diluted with saline. Docetaxel was purchased from Sanofi K.K. (Tokyo, Japan) and was diluted with saline just before administration. Paclitaxel was purchased from Wako Pure Chemical Industries, Ltd. (Osaka, Japan) as a fine powder. Paclitaxel was reconstituted with Cremophor EL-ethanol solution (1:1) and diluted tenfold with saline just before administration.
5
Combination Therapy Evaluation Protocol
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T-DM1, TRAS, and PER were provided by Chugai Pharmaceutical Co., Ltd. Human immunoglobulin G (HuIgG) was purchased from MP Biomedicals, LLC. TRAS and HuIgG were dissolved in distilled water. All agents were diluted with saline for in vivo experiments and with culture medium for in vitro experiments. CAPE, obtained from Chugai Pharmaceutical Co., Ltd., was suspended in 40Â mmol/L citrate buffer (pH 6.0) containing 5% gum Arabic as the vehicle. DM1-CH3 was purchased from Toronto Research Chemicals.
6
Bevacizumab and Capecitabine Combination Treatment
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Bevacizumab and capecitabine were provided by F. Hoffmann-La Roche (Basel, Switzerland) as a liquid and fine powder, respectively. Human immunoglobulin G (HuIgG) was purchased from MP Biomedicals (Solon, OH, USA). capecitabine was dissolved in 40 mM citrate buffer (pH 6.0) containing 5% gum arabic (capecitabine vehicle).
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