All herbs were purchased from Beijing Tongrentang Co., Ltd. (Beijing, China) and were authenticated by Xiaozhong Chen, associate professor of Heilongjiang University of Chinese medicine. D-galactose was purchased from Shanghai Macklin Biochemical Co., Ltd. Piracetam was purchased from Tianjin Jinshi Pharmaceutical Co., Ltd; The primary antibodies for Bcl-2, Caspase-1, Bax, PSD95, SYP and β-actin were purchased from Wuhan Boster Biological Technology Co., Ltd. IL-1β, IL-18 and TNF-α ELISA kits were obtained from Elabscience Biotechnology Co., Ltd. DAPI purchased from Beijing Solarbio Science & Technology Co., Ltd.
Bcl2 associated x (bax)
Manufactured by Wuhan Boster Biological Technology
Bax is a protein that plays a crucial role in the regulation of apoptosis, or programmed cell death. It is a member of the Bcl-2 family of proteins and functions as a pro-apoptotic regulator. Bax is involved in the mitochondrial pathway of apoptosis, where it can induce the release of cytochrome c and other pro-apoptotic factors from the mitochondria, leading to the activation of caspases and ultimately, cell death.
Automatically generated - may contain errors
Lab products found in correlation
Bcl 2, by Wuhan Boster Biological Technology (2 mentions)
Tnf α elisa kit, by Elabscience (1 mentions)
4 6 diamidino 2 phenylindole (dapi), by Solarbio (1 mentions)
D galactose, by Maclin Biochemical Technology (1 mentions)
Il 1β, by Elabscience (1 mentions)
β actin, by Wuhan Boster Biological Technology (1 mentions)
Rpmi 1640, by Merck Group (1 mentions)
Lc3 antibody, by Proteintech (1 mentions)
Methyl thiazolyl tetrazolium (mtt), by Merck Group (1 mentions)
Di 2 pyridylketone, by Merck Group (1 mentions)
Ferrostatin 1, by Merck Group (1 mentions)
Ferritin antibody for immunofluorescence, by Santa Cruz Biotechnology (1 mentions)
3 methyladenin 3 ma, by Merck Group (1 mentions)
Gapdh, by Wuhan Boster Biological Technology (1 mentions)
Secondary antibodies for western blotting, by EarthOx (1 mentions)
2 protocols using bcl2 associated x (bax)
1
Herbal Neuroprotection in Aging
2
Ferroptosis Pathway Regulation in HepG2 Cells
Check if the same lab product or an alternative is used in the 5 most similar protocols
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The HepG2 cell line was obtained from HonorGene; Changsha Aibiwei Biotechnology Co., Ltd. Ferrostatin-1, MTT, di-2-pyridylketone, 3-methyladenin (3-MA), RPMI-1640, and other chemicals were purchased from Sigma-Aldrich; Merck KGaA. GPx4, xCT (SLC7A11), vimentin, nuclear receptor coactivator-4 (NCOA4), and LC3 antibodies were obtained from ProteinTech Group, Inc. Antibodies against p53, caspase-8, GAPDH, Bax, and Bcl-2 were purchased from Wuhan Boster Biological Technology, Ltd. Antibodies targeting E-cadherin and secondary antibodies (fluorescence-labeled for immunofluorescence) were purchased from Cell Signaling Biotechnology, Inc. Ferritin antibody for immunofluorescence was obtained from Santa Cruz Biotechnology, Inc. NCOA4 antibody for immunofluorescence was purchased from Atlas Antibodies. Secondary antibodies for western blotting were obtained from EarthOx Life Sciences.
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