4 chloro α cyanocinnamicacid

Manufactured by Merck Group

Sourced in Germany, Italy

4-chloro-α-cyanocinnamicacid is a chemical compound used in laboratory settings. It is a white crystalline solid. The core function of this product is to serve as a building block or intermediate in the synthesis of other chemical compounds. Detailed information on its specific applications or intended uses is not provided.

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Lab products found in correlation

Ammonium hydrogen carbonate, by Merck Group (1 mentions) 1 4 dithiothreitol, by Carl Roth (1 mentions) 2 5 dihydroxybenzoic acid, by Merck Group (1 mentions) Urea, by Merck Group (1 mentions) Milli q system, by Merck Group (1 mentions) Human hemoglobin, by Merck Group (1 mentions) Proteomic grade trypsin, by Merck Group (1 mentions)

2 protocols using 4 chloro α cyanocinnamicacid

Hydroxyapatite-based Kefir Proteomics

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Hydroxyapatite
(CHT Ceramic
Type I, 40 μm) was purchased from Bio-Rad (Munich, Germany).
Formic acid (LC–MS grade), potassium chloride, 85% o-phosphoric
acid, ammonium hydrogen carbonate, 4-chloro-α-cyanocinnamic
acid, and 2,5-dihydroxybenzoic acid were obtained from Sigma-Aldrich
(Taufkirchen, Germany). Acetonitrile (LC–MS grade) was purchased
from Honeywell Fluka (Seelze, Germany) and 1,4-dithiothreitol was
purchased from Carl Roth (Karlsruhe, Germany). Tris(hydroxymethyl)aminomethane
hydrochloride and ammonia (25%) were purchased from Acros Organics
(Geel, Belgium) and urea was purchased from Merck Millipore (Darmstadt,
Germany). Alkaline phosphatase (1500 U, grade I) from calf intestine
was purchased from Roche Diagnostics (Mannheim, Germany). Purified
water was taken from a Milli-Q system (Merck Chemicals, Darmstadt,
Germany).
Three different kefir batches of the same brand were
purchased from a local supermarket. The kefir was industrially produced
from pasteurized and homogenized low-fat organic cow milk (1.5%) using
a complex culture of yeast and lactic acid bacteria.

Savastano M.L., Liu Y., Mels J., Dittrich D., Haus S., Gensberger-Reigl S, & Pischetsrieder M. (2019). Profiling of Multiphosphorylated Peptides in Kefir and Their Release During Simulated Gastrointestinal Digestion. ACS Omega, 4(5), 7963-7970.

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Mass Spectrometry Reagents Database

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Water, acetone, acetonitrile, trifluoroacetic acid (TFA), 2,2′:5′,2″-terthiophene (TER), 1,5-diaminonapthalene (DAN), trans-2-[3-(4-t-butyl-phenyl)-2-methyl-2-propenylidene]malononitrile (DCTB), 4-hydroxy-α-cyano cinnamic acid (CHCA), 4-chloro-α-cyano cinnamic acid (CClCA), Nickel(II) phthalocyanine (NiPc), Nickel(II) 2,9,16,23-tetraphenoxy-29H-31H-phthalocyanine (NiPcPhe), Cu(II) phthalocyanine (CuPc), Zinc(II) Protoporphyrin IX (ZnPP), Cobalt chloride (II) Protoporphyrin IX (CoPP), cytochrome c (horse heart), myoglobin, human hemoglobin, and proteomic-grade trypsin, were obtained from Sigma-Aldrich (Milan, Italy). Livers of cod and bovine as well as mussel were purchased from a local supermarket. Plasma was drawn from a healthy voluntary subject. All solvents used were LC–MS grade. A mass standards kit containing bradykinin (2–9 clip), angiotensin I, glu1-fibrinopeptide, ACTH (1–17, 18–39, 7–38 clips) for calibration was purchased from AB Sciex (Concord, ON, Canada).

Bianco M., Ventura G., Calvano C.D., Losito I., Cataldi T.R, & Monopoli A. (2024). Matrix Selection Strategies for MALDI-TOF MS/MS Characterization of Cyclic Tetrapyrroles in Blood and Food Samples. Molecules, 29(4), 868.

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