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Cpg oligodeoxynucleotide odn 1826 vaccigrade

Manufactured by InvivoGen
Sourced in United States

CpG oligodeoxynucleotide (ODN) 1826 VacciGrade is a synthetic DNA oligonucleotide. It contains unmethylated CpG motifs that can stimulate the innate immune system.

Automatically generated - may contain errors

2 protocols using cpg oligodeoxynucleotide odn 1826 vaccigrade

1

M2e peptide and CpG ODN vaccine

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M2e (acetylated-SLLTEVETPIRNEWGSRSNDSSDC-amidated, MW: 2736 Da) was chemically synthesized by AAPPTec, LLC, USA. CpG oligodeoxynucleotide (ODN) 1826 VacciGrade was purchased from InvivoGen (San Diego, CA, USA). CpG ODN 1826 has a sequence of 5’-TCCATGACGTTCCTGACGTT-3’ (CpG motifs are underlined) and is recognized by toll-like receptor 9 (TLR9). All secondary antibodies were purchased from Southern Biotech, USA.
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2

Consensus M2e Peptide Synthesis and Analysis

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Consensus M2e peptide (acetylated-SLLTEVETPIRNEWGSRSNDSSDC-amidated, MW: 2736 Da) was chemically synthesized by AAPPTec (Louisville, KY, USA). Underlined serines (S) are intentional substitutions of native cysteine to serine. CpG oligodeoxynucleotide (ODN) 1826 VacciGrade (5′-TCCATGACGTTCCTGACGTT-3′) was purchased from InvivoGen (San Diego, CA, USA). Alexa-Fluor 488-labeledanti-mouse IgG antibody was obtained from Life Technologies (Carlsbad, CA, USA). All other secondary antibodies were purchased from Southern Biotech (Birmingham, AL, USA).
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