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Standard laboratory chow diet

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The standard laboratory chow diet is a nutritionally balanced food formulation designed for use in laboratory animal research. It provides a consistent and complete source of essential nutrients to support the health and growth of laboratory animals.

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2 protocols using standard laboratory chow diet

1

Aging Male C57Bl/6NT Mice Study

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Adult male C57Bl/6NT mice, 8–10 months of age (Taconic, Germantown, NY) were shipped directly to Brookhaven National Laboratory (BNL, Upton, NY). Mice were fed standard laboratory chow diet (Harlan Teklad), were given water access ad libitum and kept in the temperature- and light-controlled (12 hour light/dark cycles) environment. All mice were handled in accordance with the guidelines set and approved by the Institutional Animal Care and Use Committees (IACUC) at both GeneSys Research Institute (GRI) and Brookhaven National Labs (BNL). Any animal in this study found to exhibit severe or irreversible symptoms of pain and stress (limited mobility, reduced consumption of food and water, weight loss of 15% or more) was euthanized immediately by Pentobarbital based euthanasia solution 200 mg/Kg intraperitoneal (i.p). This method is consistent with the recommendation of the Panel on Euthanasia of the American Veterinary Medical Association Guidelines on Euthanasia.
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2

Aging C57Bl/6NT Mice Welfare Protocol

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Adult male C57Bl/6NT mice, 8–10 months of age (Taconic, Germantown, NY) were used for the entire study. Animals were shipped directly to Brookhaven National Laboratory (BNL, Upton, NY) where they were fed standard laboratory chow diet (Harlan Teklad, Madison, WI), given water access ad libitum and kept in a temperature-controlled environment on a 12:12 h light-dark schedule. All mice were handled in accordance with the guidelines set and approved by the Institutional Animal Care and Use Committees (IACUC) at both GeneSys Research Institute (Boston, MA) and BNL. Any animal in this study found to exhibit severe or irreversible symptoms of pain and distress (limited mobility, reduced consumption of food and water, weight loss of 15% or more) was euthanized immediately by pentobarbital-based euthanasia solution 200 mg/kg intraperitoneal (i.p.) injection, which is consistent with the recommendation of the Panel on Euthanasia of the American Veterinary Medical Association Guidelines on Euthanasia.
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