I4000sr immunology analyzer

Manufactured by Abbott

The Abbott I4000SR Immunology Analyzer is a diagnostic instrument designed for the automated analysis of immunoassay tests. It is capable of processing a variety of immunoassay tests, including those for infectious diseases, endocrinology, and therapeutic drug monitoring. The instrument is equipped with advanced technology to provide accurate and reliable results.

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Lab products found in correlation

Au5800 chemistry analyzer, by Beckman Coulter (2 mentions)

Close spelling variants of this product

I4000SR

2 protocols using i4000sr immunology analyzer

Epigenetic Profiling of Type 2 Diabetes

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Our study was approved by the Medical Ethics Committee of Zhongnan Hospital of Wuhan University (approval number 2014039), and written informed consents were obtained from each participant. A 1:1 matched case-control samples were collected (T2DM patients = 104, controls = 108) from Zhongnan Hospital of Wuhan University. Patients were diagnosed as T2DM according to the Standards of Medical Care in Diabetes 2012 of the American Diabetes Association (ADA). The age- and gender-matched controls were randomly enrolled from healthy individuals who were free of endocrine diseases, cardiovascular diseases, and cancers. Another 11 T2DM patients and five controls participating in OGTT were also enrolled for further investigation of the dynamic regulation of 5mC and 5hmC after glucose stimulation. Biochemical parameters were determined by Beckman AU5800 chemistry analyzer with Beckman commercial kits in the clinical laboratory, including fasting blood glucose, triglycerides (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C). Blood HbA1c was detected by ADAMS HA-8160 high-performance liquid chromatography. Serum insulin was determined by Abbott i4000SR Immunology Analyzer with i2000 commercial kits. Artery ultrasound was utilized to test the presence of atherosclerotic plaque, an indicator for macrovascular diseases.

Yuan E.F., Yang Y., Cheng L., Deng X., Chen S.M., Zhou X, & Liu S.M. (2019). Hyperglycemia affects global 5-methylcytosine and 5-hydroxymethylcytosine in blood genomic DNA through upregulation of SIRT6 and TETs. Clinical Epigenetics, 11, 63.

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Comprehensive Metabolic Biomarker Analysis

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Laboratory measurements were performed at Zhongnan Hospital for the current study. Kidney function parameters (creatinine, urea nitrogen, uric acid and eGFR[19 (link)]) and serum glucose were examined by the AU5800 Chemistry Analyzer (Beckman). The HA-8160 Glycohemoglobin Analyzer (ADAMS) was used to measure blood glycated hemoglobin (HbA1c). Serum insulin was assayed by the i4000SR Immunology Analyzer (Abbott Laboratories).

Yang Y., Zeng C., Yang K., Xu S., Zhang Z., Cai Q., He C., Zhang W, & Liu S.M. (2022). Genome-wide Analysis Reflects Novel 5-Hydroxymethylcytosines Implicated in Diabetic Nephropathy and the Biomarker Potential. Extracellular vesicles and circulating nucleic acids, 3(1), 49-60.

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