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Fluoxetine flx

Manufactured by Eli Lilly
Sourced in Brazil, China

Fluoxetine (FLX) is a selective serotonin reuptake inhibitor (SSRI) used as a pharmaceutical ingredient in various medications. It functions by increasing the availability of the neurotransmitter serotonin in the brain.

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2 protocols using fluoxetine flx

1

Substances Used in Pharmacological Study

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The following substances were used in this study: methanol (MeOH), Na2CO3, AlCl3, CH3CO2K, gentamycin, amikacin, benzylpenicillin, cephalothin (Sigma Chemical Corporation, San Luis, Missouri, USA); diazepam (DZP; Neo Química®), flumazenil (Fmz; Sandoz®), dimethylsulfoxide (DMSO; Dynamic®), granisetron chloride (Gstn; Corepharma/Middlesex, NJ, USA), pizotifen maleate (Piz; Central Pharmacy of Manipulation/São Paulo, SP, Brazil), fluoxetine (Flx; Eli Lilly/Indianapolis, IN, USA), and cyproheptadine (Cypro; Evidence Pharmaceutical Solutions/Fortaleza, CE, Brazil).
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2

Icariin Alleviates Corticosterone-Induced Stress

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ICA (the purity is 98.93%) was purchased from Shanghai Ronghe Medical Science Co., Ltd. (Shanghai, China). Dimethyl sulfoxide (DMSO) was used to prepare ICA stock solutions and diluted with sterile normal saline (DMSO concentration: 0.1%) (35) . Fluoxetine (Flx) was purchased from Eli Lilly and Company (Suzhou, China) and diluted to 10 mg/mL with a sterile saline solution (36) . Mitochondria Isolation Kit for Tissue (No.89801) was bought from Thermo Fisher Scientific Inc. Rat corticosterone (CORT) ELISA kits from ebioscience (San Diego, CA) were purchased from Beyotime Biotech Inc., China. Mouse anti-GR (1:1000), mouse anti-Bcl-2, mouse anti-Bax (1:400, Santa Cruz Biotechnology, Santa Cruz, CA, USA), anti-β-actin, anti-Cox-IV, anti-caspase-3, cleaved caspase-3, anti-cytochrome C (1:1000, Bioworld Technology Co., Ltd, Nanjing, China). The tunnel was bought from Wuhan Boster Co., Ltd. (China).
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