Sas enterprise guide

The Healthdata.be platform not only enables safe data transfer but also provides a secure environment for data handling and data analysis for research purposes. Coded data are received by the HD4RES (Healthdata for research) service, which shows the data as sent by the data provider. The interface of the HD4RES is almost identical to that of the HD4DP, except that identification details are coded. Upon arrival in the HD4RES, the data are not yet stored in the datawarehouse (DWH) of Healthdata.be. The DWH has 3 separate entities—the validation environment, the analysis environment, and the reporting environment—and uses SAS Enterprise Guide (SAS Institute Inc) to visualize and process the data. It is first stored in a validation table where data quality is controlled. Healthdata.be allows for semiautomated processes so that the validation of continuous data capture can be operationalized. Once validated, data are then promoted to the analysis environment of Healthdata.be. Access to the HD4RES and the separate environments of the DWH are secured through a 2-factor authentication and can be restricted depending on the needs of the researcher. Furthermore, data processing and reporting can be operationalized to accommodate a continuous data flow in ongoing registers.

Data were analyzed using GraphPad Prism (Version 9.0; San Diego, CA, USA) and SAS Enterprise Guide (Version 7.13; Cary, NC, USA).
Subject characteristics were compared using the Mann Whitney U test. The Friedman test compared differences between ultrasound assessment using SP, HPP1, and HPP2 in the current paired design with post test results allowing for interpretation of directionality. Within-probe performance was tested via the Kruskal-Wallis test with post testing to interpret effect sizes. Post tests were adjusted for multiple comparisons. Linear regression tested dependency of measures of body size relative to ultrasound scoring. General alpha-level was set at 0.05.
One-way-ANOVA was used to test for differences in CAP between BMI groups. The cutoff for optimal visualization of the liver and right kidney as performed using the total ultrasound score was set at 32 points via calculating the mean score achieved within BMI group I, in a setting of poorer imaging quality for BMI groups II through IV across probes (unpaired t test: P < 0.0001; − 7.82 points, 95% confidence interval − 7.82±1.40 points).