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Taxus element stent

Manufactured by Boston Scientific
Sourced in United States

The Taxus Element stent is a medical device manufactured by Boston Scientific. It is a small mesh-like tube that is designed to be placed in a patient's artery to help keep the vessel open and prevent it from narrowing or closing. The stent is typically used in the treatment of coronary artery disease.

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2 protocols using taxus element stent

1

Paclitaxel-iopromide Balloon vs. DES

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The different devices are specified in Table 1. As a balloon, the polymer‐free paclitaxel‐iopromide–coated balloon SeQuent Please (B. Braun Melsungen AG, Melsungen, Germany) is used. The DES group consists of 2 stent types: the everolimus‐eluting Xience stent (Abbott Vascular, Santa Clara, CA; also distributed as the Promus stent by Boston Scientific Natick, MA), and the paclitaxel‐eluting Taxus Element stent (Boston Scientific). Initially, the study was started with the paclitaxel‐eluting Taxus Element stent as comparator to use devices with similar agents. However, after inclusion of 20% of patients, the paclitaxel‐eluting stent was no longer available.23, 24 To continue the trial, the steering committee decided to replace the initial comparator stent with the best‐in‐class later‐generation DES (ie, the everolimus‐eluting stent). Accordingly, the sample size was increased to comply with the different efficacy of the 2 comparator stents.
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2

Paclitaxel-Coated Balloon vs. Drug-Eluting Stent

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Patients randomized to DCB were treated with the paclitaxel-coated SeQuent Please or SeQuent Please Neo balloon (B. Braun Melsungen AG, Melsungen, Germany), while patients randomized to DES were treated with either the everolimus-eluting Xience stent (Abbott Vascular, Santa Clara, CA, USA) or the paclitaxel-eluting Taxus Element stent (Boston Scientific, Natick, MA, USA) (3, 4, 15). The strut thickness of both DES was 81 μm. The DCB needed to be 2 to 3 mm longer on each side than the predilatation balloon to avoid geographical mismatch, and they were inflated at a nominal pressure for at least 30 s, as recommended in the consensus documents [16 (link)]. When there were flow-limiting dissections after DCB treatment despite an acceptable result after lesion preparation, stent implantation was performed. After PCI, DAPT was given using acetylsalicylic acid (100 mg per day) and either clopidogrel (75 mg per day), prasugrel (10 mg per day), or ticagrelor (90 mg twice per day); DAPT was continued in stable patients for 4 weeks for DCB or 6 months for DES and in patients with acute coronary syndromes for 12 months. Follow-up was conducted after 12, 24 and 36 months with structured clinical questionnaires or phone calls to assess clinical events and medication. Patients were followed for a median of 3 years.
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