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Magpro stimulator

Manufactured by Medtronic
Sourced in United States

The MagPro stimulator is a laboratory device used for the application of magnetic stimulation. It provides a controlled magnetic field to stimulate specific areas of interest. The core function of the MagPro stimulator is to generate and deliver magnetic pulses, which can be used for various research and diagnostic purposes. The device offers adjustable parameters to customize the stimulation intensity and timing.

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Lab products found in correlation

3 protocols using magpro stimulator

1

Precise Localization of Motor Cortex

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Left M1 was localized by single transcranial magnetic stimulation (TMS) pulses in each participant. We used a standard figure of eight coil (MC-B70) connected to a MagPro stimulator (Medtronic, Minneapolis, MN, USA) placed tangentially to the scalp with the handle pointing backwards and laterally at about 45° away from the midline inducing an initial posterior-anterior current flow in the brain. The optimal cortical representation of the right first dorsal interosseous (FDI) muscle was localized by inducing motor-evoked potentials (MEP). By moving the coil in 0.5 cm steps anterior, posterior, medial, and lateral to this area, the exact localization of the spot which elicited the maximal FDI motor response was identified as stimulation target.
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2

Intermittent Theta Burst Stimulation Effects

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iTBS was delivered over the affected motor cortex “hot spot” for MEPs in the contralateral FDI muscle using a MagPro stimulator (Medtronic A/S Denmark) connected to a figure-of-eight coil (MCF B65). The magnetic stimulus had a biphasic waveform with a pulse width of about 280 μs and a maximum magnetic field strength of 1.5 T. The initial direction of the current induced in the brain was anterior to posterior. The stimulation intensity was defined in relation to the AMT evaluated using the MagPro stimulator. An intensity of 80% AMT was used. We applied the iTBS protocol in which 10 bursts of high frequency stimulation (3 pulses at 50 Hz) are delivered at 5 Hz every 10 s, for a total of 600 pulses (Huang et al., 2005 (link)). iTBS effects on both hemispheres were assessed by evaluating the changes of the RMT, AMT, and MEP amplitude stimulating the AH and UH, before and immediately after iTBS. MEP amplitude was evaluated as detailed above.
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3

Modulating Motor Cortex Excitability via iTBS

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iTBS was delivered over the affected motor cortex “hot spot” for MEPs in the contralateral FDI muscle using a MagPro stimulator (Medtronic A/S Denmark) connected to a figure-of-eight coil (MCF B65). The magnetic stimulus had a biphasic waveform with a pulse width of about 280 μs and a maximum magnetic field strength of 1.5 T. The initial direction of the current induced in the brain was anterior to posterior. The stimulation intensity was defined in relation to the AMT evaluated using the MagPro stimulator. An intensity of 80% AMT was used. We applied the iTBS protocol in which 10 bursts of high frequency stimulation (3 pulses at 50 Hz) are applied at 5 Hz every 10 s, for a total of 600 pulses [20 (link)].
MEP amplitude was evaluated before and immediately after iTBS using a stimulus intensity of 120% RMT with the muscle at rest. Subjects were given audio-visual feedback of their electromyographic (EMG) signal at high gain to assist them in maintaining complete relaxation; trials contaminated by EMG activity were discarded. Ten data sweeps were collected, and the mean peak-to-peak amplitude of the MEPs was calculated.
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