B6 c tg cmv cre 1cgn j cmv cre mice

C57BL/6 mice and Il25^−/− mice were obtained through a supply contract between the National Institute of Allergy and Infectious Diseases (NIAID) and Taconic Farms. Il33^−/− animals were generated by cross-breeding B6(129S4)-Il33tm1.1Bryc/J (Il33^f/f) mice and B6.C-Tg(CMV-cre)1Cgn/J (CMV-Cre) mice, both of which were purchased from The Jackson Laboratory. B6(C)-Il5^{tm1.1(icre)Lky}/J (also known as R5) mice, ROSA26LSL-tdTomato (also known as Ai14) mice, C57BL/6-Gt(ROSA)26Sor^{tm1(HBEGF)Awai}/J mice (ROSA26iDTR) mice, and Gata3tm1.1Mbu/J (Gata3^f/f) mice were purchased from The Jackson Laboratory. Dr. Warren J Leonard (NHLBI) kindly provided C57BL/6 Tslpr^−/− mice. Il4^−/− and eoCre : Il4/13^f/f mice on a C57BL/6 background have been described previously¹⁵ . All the mice used in these studies were female, 6–8 weeks old, and were bred and maintained in the NIAID animal care facility under specific pathogen-free condition. They were used under a study protocol approved by the NIAID Animal Care and Use Committee (protocol number LPD 68E). All aspects of the use of animals in this research were monitored for compliance with The Animal Welfare Act, the PHS Policy, the U.S. Government Principles for the Utilization and Care of Vertebrate Animals Used in Testing, Research, and Training, and the NIH Guide for the Care and Use of Laboratory Animals.