6545xt advancebio q tof

Manufactured by Agilent Technologies

The 6545XT AdvanceBio Q-TOF is a high-resolution quadrupole time-of-flight mass spectrometer designed for advanced biopharmaceutical characterization. It provides precise mass measurement and high-quality data for the analysis of large biomolecules.

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Lab products found in correlation

Agilent 1290 uplc, by Agilent Technologies (1 mentions)

Close spelling variants of this product

6545XT AdvanceBio Q-TOF mass spectrometer 6545XT AdvanceBio LC/Q-TOF 6545XT Q-TOF

1 protocol using 6545xt advancebio q tof

2D-LC-MS Workflow for Biomolecule Analysis

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The 2D-LC-MS system was composed of an Agilent 1290 UPLC and 6545XT AdvanceBio Q-TOF. All instrument modules were from the 1290 Infinity line from Agilent Technologies: first (1D) and second (2D) dimension binary pumps; autosampler, thermostated column compartments, ultraviolet (UV) detectors, and fraction collector. The interface valve connecting the two dimensions of the system was set up with 20 µL sample loops made from 10 cm lengths of 0.0200 i.d. PEEK tubing. The mass spectrometer 6545XT AdvanceBio Q-TOF was a time-of-flight mass spectrometer instrument equipped with an Agilent JetStream electrospray ionization source.
The Agilent 1290 UPLC and 6545XT AdvanceBio Q-TOF were controlled by MassHunter software V10.0. Data were processed by Agilent MassHunter BioConfirm V10.0. The theoretical MW was confirmed by Sequence Manger V10.0.

Jin X, & He B. (2023). Combination of On-Line and Off-Line Two-Dimensional Liquid Chromatography-Mass Spectrometry for Comprehensive Characterization of mAb Charge Variants and Precise Instructions for Rapid Process Development. International Journal of Molecular Sciences, 24(20), 15184.

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