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2 protocols using potassium acetate

1

Enzymatic Esterification of Menthol and Lauric Acid

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The DES components, (-)-menthol (purity ≥ 98.5%) and lauric acid (LA) (purity ≥ 97.5%) as well as the enzyme Candida rugosa lipase type VII ≥ 700 U/mg (CRL) were purchased from Sigma-Aldrich Chemie GmbH (Steinheim, Germany). The salts used in this study were: lithium chloride (LiCl ≥ 99%, p.a., ACS), potassium acetate (KAc ≥ 99%), sodium chloride (NaCl > 99.8%) (all from Carl Roth GmbH + Co. KG, Karlsruhe, Germany); magnesium chloride hexahydrate (MgCl2•6H2O ≥ 99%), potassium iodide (KI > 99.5%), sodium bromide (NaBr ≥ 99.5%), sodium iodide (NaI ≥ 99%, ACS), potassium carbonate (K2CO3 ≥ 99%, anhydrous, Fluka) (all from Sigma-Aldrich Chemie GmbH, Steinheim, Germany), lithium bromide (LiBr > 99%, anhydrous, Alfa Aesar, Thermo Fisher GmbH, Kandel, Germany), and potassium nitrate (KNO3 extra pure, Merck KGaA, Darmstadt, Germany). The ester standard ((-)-menthyl laurate) was kindly synthesized by the Institute of Applied Synthetic Chemistry (Research Group of Prof. Marko D. Mihovilovic, Vienna University of Technology). All chemicals were used without any additional purification or dehydration step.
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2

Preparation and Characterization of RIT-Loaded Polymer Composites

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RIT was obtained from AbbVie Deutschland GmbH & Co. KG (Ludwigshafen, Germany). The copolymer PVPVA (Kollidon®® VA64) with a weight-average molar mass of 65,000 g/mol was purchased from BASF SE (Ludwigshafen, Germany). Hydrochloric acid (10%) was purchased from AppliChem GmbH (Darmstadt, Germany), and potassium acetate (purity ≥ 99%) was purchased from Carl Roth GmbH & Co. KG (Karlsruhe, Germany). Acetone (purity ≥ 99.8%), sodium dihydrogen phosphate (purity ≥ 99%), and disodium hydrogen phosphate dihydrate (purity ≥ 99.5%) were purchased from Merck KGaA (Darmstadt, Germany). Magnesium nitrate hexahydrate (purity ≥ 98%), potassium nitrate (purity ≥ 99%), and potassium sulfate (purity ≥ 99%) were purchased from VWR International GmbH (Darmstadt, Germany). All substances were used without further purification. Water was freshly prepared with a Milli-Q®® Advantage A10 purification system from Merck KGaA (Darmstadt, Germany).
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