Pomalidomide

Manufactured by Abcam

Pomalidomide is a small molecule compound that can be used for various research applications. It functions as an immunomodulatory agent. The core activity of Pomalidomide is to modulate the immune system.

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Lab products found in correlation

4 6 diamidino 2 phenylindole (dapi), by Merck Group (1 mentions) Lenalidomide, by Abcam (1 mentions) Cc 885, by MedChemExpress (1 mentions)

2 protocols using pomalidomide

Western Blot, IHC, and IF Protocols

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Antibodies used for Western blotting, immunohistochemistry and immunofluorescence are described in detail in Supplemental Table 1. IRF4-shRNA plasmid (TL315501) and IRF4 (NM_002460) human cDNA ORF clone (RC204876) were purchased from Origene (Rockville, MD). Recombinant human IL-4 was purchased from ThermoFisher Scientific (Waltham, MA). DAPI was from Sigma-Aldrich (St. Louis, MO). Pomalidomide was from Abcam (Cambridge, MA). All other chemicals were from ThermoFisher Scientific.

Bastea L.I., Liou G.Y., Pandey V., Fleming A.K., von Roemeling C.A., Doeppler H., Li Z., Qiu Y., Edenfield B., Copland J.A., Tun H.W, & Storz P. (2019). Pomalidomide alters pancreatic macrophage populations to generate an immune-responsive environment at precancerous and cancerous lesions. Cancer research, 79(7), 1535-1548.

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Comprehensive Characterization of Novel IMiD Compounds

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Lenalidomide (Abcam), pomalidomide (Abcam),
Avadomide/CC-122, (Aquila Pharmatech), Iberdomide/CC-220 (MedChem
Express), Mezigdomide/CC-92480 (WuXi AppTec), CC-90009 (WuXi AppTec),
CC-885 (MedChem Express), and MLN4924 were purchased from the indicated
suppliers and were subjected to in-house LC-MS for quality control.

Sialana F.J., Roumeliotis T.I., Bouguenina H., Chan Wah Hak L., Wang H., Caldwell J., Collins I., Chopra R, & Choudhary J.S. (2022). SimPLIT: Simplified Sample Preparation for Large-Scale Isobaric Tagging Proteomics. Journal of Proteome Research, 21(8), 1842-1856.

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