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Docetaxel taxotere

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Sourced in France

Docetaxel (Taxotere) is a cytotoxic chemotherapy drug used to treat various types of cancer. It belongs to the class of drugs known as taxanes and is used to inhibit cell division and promote cell death in rapidly dividing cancer cells.

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Lab products found in correlation

Gemzar, by Eli Lilly (1 mentions) Adriamycin, by Pfizer (1 mentions) Pe anti human cd340 erbb2 her2 antibody, by BioLegend (1 mentions) Cytotox glo, by Promega (1 mentions) Recombinant human heregulin β1, by Thermo Fisher Scientific (1 mentions) Celltrace carboxyfluorescein succinimidyl ester cfse cell proliferation kit, by Thermo Fisher Scientific (1 mentions) Celltiter blue, by Promega (1 mentions) Human vegf quantikine elisa kit, by R&D Systems (1 mentions) Caspase glo 3 7 assay kit, by Promega (1 mentions) Anisomycin, by Merck Group (1 mentions) U73343, by Merck Group (1 mentions) Gemcitabine gemzar, by Eli Lilly (1 mentions) Bms 754807, by Selleck Chemicals (1 mentions) Wortmannin, by Merck Group (1 mentions) Q vd oph, by R&D Systems (1 mentions) Pd98059, by Selleck Chemicals (1 mentions) Abt 737, by Selleck Chemicals (1 mentions) Ionomycin, by Merck Group (1 mentions) Puromycin, by Merck Group (1 mentions) Thapsigargin, by Merck Group (1 mentions)

3 protocols using docetaxel taxotere

1

Doxorubicin, Gemcitabine, and Docetaxel Protocol

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Doxorubicin (Adriamycin; Pfizer, New York, NY, USA) and gemcitabine (Gemzar; Eli Lilly and Company, Neuilly-sur-Seine, France) were obtained from the pharmacy of the Institut Bergonié (Bordeaux, France). Docetaxel (Taxotere; Sanofi-Aventis, Gentilly, France) was obtained from Sigma Aldrich (#01885, St. Quentin Fallavier, France).
Mauduit O., Brulard C., Lesluyes T., Delcroix V., Pérot G., Choublier N., Michaud M., Baud J., Lagarde P., Aurias A., Coindre J.M., Lartigue L., Blay J.Y, & Chibon F. (2019). RCBTB1 Deletion Is Associated with Metastatic Outcome and Contributes to Docetaxel Resistance in Nontranslocation-Related Pleomorphic Sarcomas. Cancers, 11(1), 81.
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2

Evaluation of ErbB2/HER2 Biosimilar Candidates

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The reference products in this study were selected randomly from 154 lots of EU- and US-sourced reference product. The CellTiter-Blue® and CytoTox-Glo® kits were obtained from Promega (Madison, WI, USA). The phycoerythrin (PE) anti-human CD340 (ErbB2/HER2) antibody was obtained from Biolegend (San Diego, CA, USA). The ErbB2/HER2 enzyme-linked immunosorbent assay (ELISA) kit was obtained from R&D Systems (Minneapolis, MN, USA), the Phospho-Akt (Ser473) ELISA kit was obtained from Cell Signaling Technology (Danvers, MA, USA), and the Human VEGF Quantikine® ELISA kit was obtained from R&D Systems. The CellTrace™ carboxyfluorescein succinimidyl ester (CFSE) Cell Proliferation Kit was obtained from Thermo Fisher Scientific (Waltham, MA, USA), the docetaxel (Taxotere®) was obtained from Sanofi-Aventis (Paris, France), and the PathHunters® Flash Detection Kit was obtained from DiscoverX (Fremont, CA, USA). The recombinant human heregulin-β1 was obtained from Peprotech (Seoul, South Korea) and the Caspase-glo 3/7 assay kit was obtained from Promega.
Paek K., Kim G.W., Ahn S.Y., Lim J.H., Jung D., Kim S, & Lee J.H. (2019). Assessment of the Molecular Mechanism of Action of SB3, a Trastuzumab Biosimilar. Biodrugs, 33(6), 661-671.
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3

Evaluation of Anticancer Drug Combinations

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Doxorubicin (Adriamycin; Pfizer, New York, NY, USA) and gemcitabine (Gemzar; Eli Lilly and Company, Neuilly-sur-Seine, France) were obtained from the pharmacy of the Bergonié Institute (Bordeaux, France). Docetaxel (Taxotere; Sanofi-Aventis, Gentilly, France) was obtained from Sigma-Aldrich (St. Quentin Fallavier, France). ABT-737 was purchased from Selleckchem (Munich, Germany).
About the other chemicals—thapsigargin, puromycin, anisomycin, ionomycin, Hyp9, OAG, U73343, and Wortmannin—were from Sigma-Aldrich. BMS-754807 and PD98059 were purchased from Selleckchem. Larixyl acetate was obtained from Santa Cruz Biotechnology (Dallas, TX, USA). Pyr3 was from Calbiochem (Merck Millipore, Darmstadt, Germany). Human IGF1 was from Miltenyi Biotec (Paris, France). QVD-OPh was purchased from R&D Systems (Minneapolis, MN, USA).
Delcroix V., Mauduit O., Tessier N., Montillaud A., Lesluyes T., Ducret T., Chibon F., Van Coppenolle F., Ducreux S, & Vacher P. (2018). The Role of the Anti-Aging Protein Klotho in IGF-1 Signaling and Reticular Calcium Leak: Impact on the Chemosensitivity of Dedifferentiated Liposarcomas. Cancers, 10(11), 439.
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