Anti cd107a pe id4b

Manufactured by BioLegend

Anti-CD107a PE (ID4B) is a fluorescent-labeled antibody that binds to the CD107a protein, also known as LAMP-1. It is commonly used as a marker for the detection and analysis of degranulation, a process where cytotoxic cells release their cytoplasmic granules upon activation.

Automatically generated - may contain errors

Lab products found in correlation

Monensin, by BioLegend (1 mentions)

Spelling variants of this product

Anti-CD107a (26 citations) CD107a-PE (8 citations) Anti-CD107a-PE (6 citations)

2 protocols using anti cd107a pe id4b

Tumor Immune Cell Profiling

Check if the same lab product or an alternative is used in the 5 most similar protocols

Mice were injected intravenously (i.v.) with 250 μl of a solution containing 25 μg anti-CD107a PE (ID4B, Biolegend) and 10 μg monensin (Biolegend) in PBS 4 hours before mice were euthanized. Tumor tissue was then isolated, dissociated into single cell suspensions, stained with cell surface antibodies, and analyzed by flow cytometry as described above.

Chibaya L., Murphy K.C., DeMarco K.D., Gopalan S., Liu H., Parikh C.N., Lopez-Diaz Y., Faulkner M., Li J., Morris JP I.V., Ho Y.J., Chana S.K., Simon J., Luan W., Kulick A., de Stanchina E., Simin K., Zhu L.J., Fazzio T.G., Lowe S.W, & Ruscetti M. (2023). EZH2 inhibition remodels the inflammatory senescence-associated secretory phenotype to potentiate pancreatic cancer immune surveillance. Nature cancer, 4(6), 872-892.

+ Open protocol

+ Expand

Investigating Tumor-Infiltrating Lymphocytes

Check if the same lab product or an alternative is used in the 5 most similar protocols

Mice were injected intravenously with 250 μL of a solution containing 25 μg anti-CD107a PE (ID4B, Biolegend) in 1X PBS 3 hours before mice were euthanized. Pancreas tumor tissue was then isolated, dissociated, stained with cell surface antibodies, and analyzed by flow cytometry as described above.

Ruscetti M., Morris JP I.V., Mezzadra R., Russell J., Leibold J., Romesser P.B., Simon J., Kulick A., Ho Y.J., Fennell M., Li J., Norgard R.J., Wilkinson J.E., Alonso-Curbelo D., Sridharan R., Heller D.A., de Stanchina E., Stanger B.Z., Sherr C.J, & Lowe S.W. (2020). Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer. Cell, 181(2), 424-441.e21.

+ Open protocol

+ Expand

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Revolutionizing how scientists
search and build protocols!