All MRI examinations were carried out on a 3T MRI scanner without the use of intravenous gadolinium-based contrast agents. (Intera Achieva 3T, Philips Medical System, Best, The Netherlands). Multiparametric imaging sequence parameters included multiplanar SPIR (spectral presaturation with inversion recovery) fat-suppressed T1-weighted (T1W) imaging, T2-weighted (T2W) single-shot turbo spin-echo (SSH-TSE) imaging, SPAIR (spectral attenuated inversion recovery) fat-suppressed T2W SSH-TSE imaging, and diffusion-weighted imaging (DWI). SPIR T1W MRI only in the axial plane, T2W SSH-TSE imaging in three planes, and SPAIR T2-weighted SSH-TSE imaging in the axial and coronal planes were performed in all patients. DWI was performed using a single-shot spin-echo echo-plana imaging sequence with a chemical shift-selected pulse sequence (TR/TE 2200-4000/90-120). Images were acquired using a motion-proving gradient pulse of the same strength applied sequentially along three orthogonal directions) with the use of two b values (0 and 1000 s/min2). Apparent diffusion coefficient (ADC) values were determined using the two b values, as mentioned earlier.
Intera achieva 3t
Manufactured by Philips
Sourced in Netherlands
The Intera Achieva 3T is a magnetic resonance imaging (MRI) system manufactured by Philips. It is a 3-tesla strength superconducting MRI scanner designed for clinical and research applications. The Intera Achieva 3T provides high-resolution imaging capabilities for various anatomical structures and pathologies.
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10 protocols using intera achieva 3t
1
Multiparametric MRI Protocol for 3T Imaging
2
Dynamic Contrast-Enhanced MRI of Radiofrequency Ablation
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MR experiments were performed four days after RFA. All MR images were acquired using a 3.0 T MRI scanner (Intera Achieva 3T, Philips Medical Systems, Best, The Netherlands) with an extremity coil. Before MR experiments, rabbits were sedated and intravenous access was acquired via a marginal ear vein for injection of contrast agent. High spatial resolution coronal T2‐weighted MR images were acquired using a turbo spin echo (TSE) sequence (TE / TR = 80 / 3300 ms , turbo factor = 10 , FOV = 120 mm × 120 mm , matrix = 512 × 512 , slice thickness = 2 mm acquisition time = 5 − 6 min TE / TR = 4.5 / 2.3 ms , turbo factor = 30 , FOV = 120 mm × 120 mm , matrix = 160 × 160 , slice thickness = 2 mm , flip angle = 12 ∘ sampling interval = 2.4 s
3
Radiographic Monitoring of RFA Outcomes
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All patients underwent unenhanced and contrast-enhanced CT scans prior to RFA. Of the 51 patients, 48 patients were evaluated using unenhanced and contrast-enhanced CT scans after RFA. The remaining 3 patients underwent unenhanced and contrast-enhanced MRI for follow-up, and < 0.5 mmol/kg of contrast material was intravenously injected. The follow-up period after RFA occurred between February 2010 and January 2016 (median, 26 months; range, 4–60 months). All patients underwent CT scans before RF ablation. Pre-RFA and post-RFA CT examinations were performed in 1 of 3 CT scanners (GE LightSpeed VCT, GE Healthcare, Milwaukee, WI, USA; Brilliance 40, Philips Medical Systems, Cleveland, OH, USA; Aquilion, Toshiba Medical Systems Corp.). MRI examination was performed in a 3-tesla MRI scanner (Intera Achieva 3T; Philips Medical Systems, Best, the Netherlands). CT or MRI was performed 1, 6, 12, 18, and 24 months after RFA and every year thereafter.
4
Gadoxetic Acid-Enhanced MRI Protocol
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All MR images were acquired using a 3.0 Tesla (T) whole-body MR imaging system (Intera Achieva 3T, Philips Healthcare, Best, the Netherlands) equipped with a dual source parallel radiofrequency transmission system and a quadrature body coil. For gadoxetic acid (Primovist; Bayer Healthcare, Berlin, Germany)–enhanced MR imaging, unenhanced, enhanced arterial phase (20–35 seconds), portal venous phase (60 seconds), delayed phase (3 minutes), and 20 minutes HBP images were obtained using a T1-weighted three-dimensional (3D) turbo-field-echo sequence (T1 high-resolution isotropic volume examination, THRIVE; Philips Healthcare). All patients were the cubital vein injected with gadoxetic acid at a total dose of 0.025 mmol/kg body weight into, followed by a 20-mL saline flush.
5
Dynamic Contrast-Enhanced MRI Protocol
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All MRI images were acquired using a 3.0-T MRI scanner (Intera Achieva 3T, Philips Medical Systems, Best, the Netherlands) with an eight-channel sensitivity-encoding head coil. High-spatial-resolution axial T2*-weighted echo planar images were acquired using the following sequence parameters: repetition time (TR)=1,720 ms, echo time (TE)=35 ms, field of view (FOV)=240×240 mm, matrix=256×256, slices= 50, slice thickness=5.0 mm, gap=1.5 mm, number of dynamic scans=50, and temporal resolution=1.8 s. Baseline images were acquired for 10 dynamic scans, followed by the automatic injection of gadolinium-based contrast agent (0.1 mmoL/kg; Gadovist, Bayer HealthCare Pharmaceuticals, Berlin, Germany) at a rate of 3 mL/s through an 18G intravenous catheter, followed by a 40-mL normal saline flush with additional data acquisition. High-spatial-resolution sagittal T1-weighted images were acquired using the following scan parameters before injecting the contrast agent: TR=10 ms, TE=4.6 ms, FOV=240×240 mm, matrix=480×480, slices=360, slice thickness=0.5 mm.
6
Multiparametric MRI Cervix Imaging
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All MRI examinations were scanned on a 3T whole-body MRI scanner (Intera Achieva 3T, Philips Medical System, Best, the Netherlands) using phased-array techniques involving pelvic or torso phased-array coils. Multiparametric imaging sequence parameters (Table S1 in the Supplementary Appendix) included multiplanar T2W, T1-weighted (T1W), and DW imaging with multiple b value (0-800 s/mm2) of the cervix. Gadopentetate dimeglumine contrast (Magnevist; Schering, Berlin, and Germany) in all the patients was administered intravenously at a weight-based dosing of 0.2 ml/kg with a bolus injection rate of 2 ml/sec using an automatic injector, which was followed by a 20-ml saline bolus injection.
7
3T MRI Brain Imaging Protocol
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We acquired images in a 3T-Achieva-Intera magnetic resonance scanner–Philips, in a T1 volumetric sequence, according to the following parameters: isotropic voxels of 1mm3, acquired in sagittal plane (1mm of thickness; flip angle: 8°; repetition time: 7.1ms; echo time: 3.2ms; matrix: 240x240; and field-of-view: 240x240 mm).
8
fMRI Study of Cognitive Processes
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The MRI session took place at the Dartmouth Brain Imaging Center using a Phillips 3 T Achieva Intera with a 32 channel SENSE head coil. For the functional runs, there were six (2[run]x[3 content type]) runs of 148 volumes per run for a total of 888 functional (T2*) volumes with a TR of 2.5 s. The functional scans were collected using gradient-echo EPI with 42 Philips interleaved transverse slices at 3 mm per slice (TE = 35, flip angle = 90 degrees).
9
Multi-modal MRI of the Brain
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Magnetic Resonance Imaging (MRI) was performed on 3-Tesla scanner (Achieva 3T Intera, Philips Healthcare, The Netherlands) equipped with 80 mT/m gradients (maximum amplitude), rise time of 200 mT/m/ms and a dedicated 8-channel head coil. The MR protocol included a T1-weighted high-resolution sequence obtained using a three dimensional magnetization prepared rapid acquisition gradient-echo (MPRAGE) sequence with the following parameters: TR = 500 (ms), TE = 50 (ms), flip angle = 8°, FOV = 256 × 240 mm2, acquisition and reconstruction voxel size = 1 × 1 × 1.2 mm3. Diffusion-weighed imaging was performed using a spin-echo (SE) echo-planar (EPI) single shot sequence with interleaved slice acquisition and the following parameters: FOV = 240x240, matrix = 94x94 voxel, TE = 89 ms, TR = 7774 ms, slice thickness = 2.5 mm, 60 slices, no gap, SENSE reduction factor R = 2. Two distinct b-values (1000 s/mm2 and 2500 s/mm2) were applied in 64 non coplanar and non collinear directions (32 for each non-zero b-value), for diffusion weighting. In addition, eight non diffusion-weighted reference images (b0 images) were acquired.
10
Multimodal MRI Protocol for Neuroimaging
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MRI was performed with a 3 T system (Achieva 3 T Intera, Philips Healthcare, Best, The Netherlands) using an 8‐channel phased array head coil. The gradient amplitude and rise time were 80 mT/m and 200 mT/m/ms, respectively. For all subjects, the MRI acquisition protocol included an axial T2‐weighted turbo spin echo sequence, axial T2‐fluid attenuated inversion recovery, sagittal T1‐weighted turbo spin echo sequence, and a T1‐3D fast field echo sequence, which were used by expert neuroradiologists to exclude neuroradiological abnormalities. DWI was acquired using a spin–echo (SE) echo‐planar (EPI) single‐shot sequence with the following parameters: acquisition matrix, 94 × 94; field of view, 24 × 24 cm2; repetition time/echo time, 7774 ms/89 ms; slice thickness, 2.5 mm; slices, 60; and no gap; gradient duration δ (ms) 35; diffusion time Δ (ms) = 44. Three different b values (0, 1000, and 2500 s/mm2) were used. Thirty‐two noncoplanar and noncollinear directions were chosen for diffusion‐weighed imaging (b = 1000, 2500 s/mm2), and eight non‐diffusion‐weighted reference images (b = 0 s/mm2) were also collected. The SENSE (SENSitivity Encoding) imaging option with a scan time reduction factor of 2 was used. The total scan time was 35 min.
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