Acacetin

Manufactured by MedChemExpress

Acacetin is a chemical compound that functions as a flavonoid. It is a crystalline solid and is used in various research applications.

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Lab products found in correlation

Gap27, by MedChemExpress (1 mentions) Lipopolysaccharides (lps), by Merck Group (1 mentions) Pdgf bb, by MedChemExpress (1 mentions) Sds page protein loading buffer 5, by Beyotime (1 mentions) Rpmi 1640, by Thermo Fisher Scientific (1 mentions) Matrigel basement membrane matrix, by Corning (1 mentions)

3 protocols using acacetin

Acacetin, LPS, and Gap27 Protocol

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Acacetin (MedChemExpress, molecular weight: 284.26 g/mol), LPS (Sigma, 055:B5, L2880), and Gap27 (MedChemExpress) were used in the experiments.

Ouyang Y., Rong Y., Wang Y., Guo Y., Shan L., Yu X., Li L., Si J., Li X, & Ma K. (2021). A Systematic Study of the Mechanism of Acacetin Against Sepsis Based on Network Pharmacology and Experimental Validation. Frontiers in Pharmacology, 12, 683645.

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Acacetin and PDGF-BB for Liver Fibrosis Study

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Acacetin was purchased from MedChemExpress (No: Acacetin.html">HY-N0451), and Platelet-derived growth factor-BB (PDGF-BB) (MedChemExpress, No: HY-P7055) was purchased from Novus PDGF-BB, as the activator of HSCs, mimics the liver fibrosis microenvironment and maintains the activation state of HSCs [18 (link)].

Hu X., Shen H., Liu R., Tang B, & Deng F. (2024). Mechanism of acacetin regulating hepatic stellate cell apoptosis based on network pharmacology and experimental verification. Heliyon, 10(7), e28693.

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Acacetin-Induced Antiproliferative Effects

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RPMI-1640 was purchased from Gibco, 2457402; Fetal bovine serum was purchased from Viva cell, 2209058; 3-^{4,5-dimethylthiazol-2-yl}-2,5-diphenyl tetrazole bromide (MTT) was purchased from Suolarbio, M8180; Dimethyl sulfoxide (DMSO) was purchased from Mreda, M1538; Propidium iodide of cell cycle was purchased from Invitrogen, 2238888; RNase was purchased from ATRANS, GE101-01; The cell apoptosis kit was purchased from Suolarbio, CA1020; The matrigel basement membrane matrix was purchased from Corning, 356234; SDS-PAGE protein loading buffer (5×) was purchased from Beyotime, P0015L; Acacetin was purchased from MedChemExpress (MCE), HY-N0451.

Li J., Zhong X., Zhao Y., Shen J., Xiao Z, & Pilapong C. (2024). Acacetin inhibited non-small-cell lung cancer (NSCLC) cell growth via upregulating miR-34a in vitro and in vivo. Scientific Reports, 14, 2348.

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