Weight and height were measured in triplicate with mean value used in analysis. Weight was measured with subjects in light clothing on a digital electronic scale (Seca, Munich, Germany) to the nearest 0.1 kg. Standing height was measured to the nearest 0.1 cm on a stadiometer (Holtain Ltd., Crymych, UK). The validated self-assessment questionnaire developed by Morris and Udry was used for pubertal assessment, with completion by the subject with parental assistance if needed.31 Pubertal assessment was based on pubic hair in both sexes as self-assessment of breast Tanner stage in obese girls may be unreliable. The left hand wrist radiograph was compared to Greulich and Pyle standard tables to obtain bone age assessment.32 Body composition was obtained by whole body DXA using the Discovery bone densitometer (Hologic, Inc., Bedford, MA) using software version 13.3 to estimate subtotal (whole body less head) fat-free mass, fat mass, and bone mass. DXA estimated abdominal visceral and subcutaneous fat were also measured.33 Muscle density (mg/cm3) was obtained from pQCT measurement of calf muscle at the 66% site and used as a surrogate measure of intramuscular adipose tissue, which is inversely related to muscle density.
Discovery bone densitometer
Manufactured by Hologic
Sourced in United States
The Discovery bone densitometer is a medical imaging device designed to measure bone mineral density. It uses low-dose X-ray technology to provide accurate and precise measurements of bone mass, which can be used to diagnose and monitor bone-related conditions such as osteoporosis.
Automatically generated - may contain errors
Lab products found in correlation
4 protocols using discovery bone densitometer
1
Anthropometric and Body Composition Measurements
2
Body Composition and Cognitive Status
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
All patients underwent body composition measurement including lean body mass (LBM), total fat weight (TFW), and body mass index (BMI) using dual-energy X-ray absorptiometry (Discovery Bone Densitometer; Hologic, Bedford, MA) 24 (link) .
The duration between body component measurements and evaluation of CS was ≤2 weeks.
The duration between body component measurements and evaluation of CS was ≤2 weeks.
3
Quantifying Body Composition and Aerobic Capacity
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
At baseline, 3, 6, and 18 months, all participants underwent a cycling-based graded exercise test to quantify peak aerobic capacity (VO2peak) and peak power. All participants also underwent a dual-energy X-ray absorptiometry (DXA) scan, using a Hologic Discovery Bone Densitometer (Hologic, USA), in order to quantify volume of fat, muscle, and bone tissue in the body.
4
Bone Biomarkers and Osteoporotic Fractures
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
A blood sample was collected during the first three days of hospitalization, 20.0 ± 5.9 days (mean ± SD) after fracture occurrence, in the morning after an overnight fast. In each subject we evaluated 25-hydroxyvitamin D by an immunoenzymatic assay (coefficient of variation intrassay <8%; interassay <10%) (IDS Inc., Fountain Hills, AZ, USA), PTH by two-site chemiluminescent enzyme-labelled immunometric assay (coefficient of variation intraassay 5.7%, interassay 8.8%) (DPC Inc., Los Angeles, CA, USA), total calcium (by a photometric color test), phosphate, albumin, magnesium, and creatinine. GFR was estimated by the 4-variable Modification of Diet in Renal Disease (MDRD) Study equation.
In all 405 women we assessed BMD at the nonfractured femoral neck by DXA (Hologic Discovery bone densitometer, USA) on the same day as the blood sample collection. The results were recorded as T-scores (the reference population was derived from the third National Health and Nutrition Examination Survey). The coefficient of variation within subjects calculated from two repeated measurements with repositioning was 1%. Body weight and height were measured in each subject and body mass index (BMI) was calculated as weight/height 2 .
None of the patients included in the study had begun specific treatment with drugs for osteoporosis after fracture occurrence before the DXA and laboratory assessment.
In all 405 women we assessed BMD at the nonfractured femoral neck by DXA (Hologic Discovery bone densitometer, USA) on the same day as the blood sample collection. The results were recorded as T-scores (the reference population was derived from the third National Health and Nutrition Examination Survey). The coefficient of variation within subjects calculated from two repeated measurements with repositioning was 1%. Body weight and height were measured in each subject and body mass index (BMI) was calculated as weight/height 2 .
None of the patients included in the study had begun specific treatment with drugs for osteoporosis after fracture occurrence before the DXA and laboratory assessment.
About PubCompare
Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.
We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.
However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.
Ready to get started?
Sign up for free.
Registration takes 20 seconds.
Available from any computer
No download required
Revolutionizing how scientists
search and build protocols!