Sodium tetrachloroaurate 3 dihydrate

Manufactured by Merck Group

Sourced in United States

Sodium tetrachloroaurate(III) dihydrate is a chemical compound with the formula Na[AuCl4]·2H2O. It is a gold-colored crystalline solid that is used as a precursor in the synthesis of other gold compounds. The compound contains gold in the +3 oxidation state.

Automatically generated - may contain errors

Lab products found in correlation

Spelling variants of this product

Sodium tetrachloroaurate dihydrate (2 citations)

11 protocols using sodium tetrachloroaurate 3 dihydrate

Synthesis and Characterization of Gold(III) Complexes

Check if the same lab product or an alternative is used in the 5 most similar protocols

Example 1

Sodium tetrachloroaurate(III) dihydrate, sodium dimethyldithiocarbamate monohydrate, sodium diethyldithiocarbamate trihydrate, sodium dibenzyldithiocarbamate hydrate, 2,2′-bipyridine, 5,5′-dimethyl-2,2′-bipyridine and 6,6′-dimethyl-2,2′-bipyridine were purchased from Sigma-Aldrich Co. St. Louis, Mo. United States. All solvents including ethanol and dichloromethane were purchased from Merck Darmstadt, Germany, and used without further purification. All reactions were carried out under ambient conditions.

Elemental analyses of gold(III) compounds 1 to 9 were performed on Perkin Elmer Series 11 (CHNS/O) Analyzer 2400. The solid state FTIR spectra of free ligands and their corresponding gold(III) compounds were recorded on a Perkin-Elmer FTIR 180 spectrophotometer or NICOLET 6700 FTIR using potassium bromide (KBr) pellets over the range 4000-400 cm⁻¹.

¹H and ¹³C NMR spectra were recorded on a LAMBDA 500 spectrophotometer operating at 500.01, 125.65 and 200.0 MHz, respectively, in a magnetic field of 11.74 T. The nucleus observed at 500 MHz. Tetramethylsilane (TMS) was used as an internal standard for ¹H and ¹³C. The ¹³C NMR spectra were obtained with ¹H broadband decoupling, and the spectral conditions were: 32 k data points, 0.967 s acquisition time, 1.00 s pulse delay, and 45° pulse angle.

US10385072B2. Gold(III) complexes as anticancer agents and a method of treating cancer (2019-08-20). King Fahd University of Petroleum and Minerals [SA]. Inventors: Anvar Husain Abdul Kadir Isab [SA], Muhammad Altaf [SA].

+ Open protocol

+ Expand

Immunoassay for Prostate-Specific Antigen

Check if the same lab product or an alternative is used in the 5 most similar protocols

Multi-Wall Carbon Nanotubes (MWCNT) with purity 95% (8 nm of diameter) and 10–30 μm length were purchased to Cheap Tubes Inc. (Cambridgeport, USA). Nitric acid (65%) from Panreac was employed to functionalize and purify the carbon nanotubes. Purified mouse monoclonal PSA antibody (Ab) (Purified IgG-Ab) and native human PSA purified were purchased from Bio-Rad Laboratories (Munich, Germany).
Potassium dihydrogen phosphate (KH₂PO₄) and dipotassium hydrogen phosphate (K₂HPO₄) obtained from Merck and VWR Chemicals, respectively, were used to prepare phosphate buffer solutions (0.01 M PBS, pH = 7.2 and 0.1 M PBS, pH = 7.2) to dissolve the immunoreagents and as electrolyte, unless otherwise noted. Ferrocenium hexafluorophosphate (Fc-97%), employed as redox probe was purchased from Sigma Aldrich. All the solutions were prepared using ultrapure water (18 MOhm·cm, Purelab Ultra Elga equipment). The gases N₂ (99.999%) and H₂ (99.999%) were provided by Air Liquide.
Reagents employed in the gold nanoparticles synthesis included sodium tetrachloroaurate (III) dihydrate (NaAuCl₄·2H₂O, 99%), poly-n-vinylpyrrolidone (PVP, 40K), sodium hydroxide (NaOH, 99,99% purity), anhydrous ethylene glycol and methanol (+98%) and were purchased from Sigma-Aldrich.

Quintero-Jaime A.F., Berenguer-Murcia Á., Cazorla-Amorós D, & Morallón E. (2019). Carbon Nanotubes Modified With Au for Electrochemical Detection of Prostate Specific Antigen: Effect of Au Nanoparticle Size Distribution. Frontiers in Chemistry, 7, 147.

+ Open protocol

+ Expand

Synthesis of Functional Nanomaterials

Check if the same lab product or an alternative is used in the 5 most similar protocols

Copper(II) sulfate pentahydrate (CuSO₄·5H₂O), sodium tetrachloroaurate(III) dihydrate (NaAuCl₄·2H₂O), iron(III) chloride hexahydrate (FeCl₃·6H₂O), iron(II) chloride tetrahydrate (FeCl₂·4H₂O), silicon dioxide (SiO₂), (3-glycidyloxypropyl)trimethoxysilane, polyvinylpyrrolidone (PVP, MW ~ 10,000), imidazole, propargyl bromide, chlorodiphenylphosphine, sodium borohydride (NaBH₄), methyl orange (MO), sodium azide, 3-chloro-1,2-propanediol, ascorbic acid, rhodamine B (RhB), nitro compounds, methyl red (MR), and tetracycline (TC) were purchased from Sigma-Aldrich, Acros and Merck MilliporeSigma.

Gholinejad M., Bashirimousavi S, & Sansano J.M. (2024). Novel magnetic bimetallic AuCu catalyst for reduction of nitroarenes and degradation of organic dyes. Scientific Reports, 14, 5852.

+ Open protocol

+ Expand

Synthesis and Characterization of Gold Nanoparticles

Check if the same lab product or an alternative is used in the 5 most similar protocols

Freshly dried and pulverised green rooibos plant material was generously donated by the South African Rooibos Council, while pure aspalathin was isolated in house. Analytical grade metal salt and acid were used as precursors. Sodium tetrachloroaurate (III) dihydrate (NaAuCl₄·H₂O, 99.99%), the gold standard, silver nitrate salts, silver standard and polyethene glycol was supplied by Sigma-Aldrich (Cape Town, South Africa), while Milli-Q deionised water used was produced in house.

Akinfenwa A.O., Abdul N.S., Docrat F.T., Marnewick J.L., Luckay R.C, & Hussein A.A. (2021). Cytotoxic Effects of Phytomediated Silver and Gold Nanoparticles Synthesised from Rooibos (Aspalathus linearis), and Aspalathin. Plants, 10(11), 2460.

+ Open protocol

+ Expand

Synthesis and Characterization of Gold Nanoparticles

Check if the same lab product or an alternative is used in the 5 most similar protocols

Sodium tetrachloroaurate(III) dihydrate (99%), bovine serum albumin (98%), cetyltrimethylammonium bromide (CTAB), m ethanol (99.5%), ethanol (99.5%), paraformaldehyde, phosphotungstic acid hydrate, pimonidazole HCl, doxorubicin, hematoxylin and eosin were obtained from Sigma-Aldrich (St. Louis, MO, USA). Phosphate buffered saline (PBS), fetal bovine serum, RPMI 1640 medium, Dulbecco's modified Eagle's medium (DMEM) were obtained from GIBCO (Grand Island, NY, USA). Penicillin-streptomycin, trypsin-ethylenediaminetetraacetic acid, 4',6-diamidino-2-phenylindole, dihydrochloride (DAPI), Hochest 33342, transferrin-Alexa 633 and tetramethylrhodamine isothiocyanate (TRITC) were bought from invitrogen (Invitrogen, Carlsbad, CA, USA). Alamar blue® was purchased from AbD Serotec (Oxford, UK). Deionized water (18.2 MΩ. cm) was used to prepare all of the aqueous solutions. For the cellular experiments, all of the equipment and deionized water was steamed at 134 ℃ in 15 min by autoclave (TAT-202A20, EQUS, Taiwan) before any use.

Chiu H.T., Su C.K., Sun Y.C., Chiang C.S, & Huang Y.F. (2017). Albumin-Gold Nanorod Nanoplatform for Cell-Mediated Tumoritropic Delivery with Homogenous ChemoDrug Distribution and Enhanced Retention Ability. Theranostics, 7(12), 3034-3052.

+ Open protocol

+ Expand

Biogenic Synthesis of Gold Nanoparticles

Cited 1 time

Check if the same lab product or an alternative is used in the 5 most similar protocols

AuNPs were synthesized following a protocol described by Elbagory et al. [70 (link)] with slight modifications. In a 96 well polystyrene microplates, 250 µL of 1 mM of sodium tetrachloroaurate(III) dihydrate (Sigma-Aldrich, St Louis, USA) was added to 50 µL of plant extract stock solutions at varying concentrations (0.78–50 mg/mL) to a final volume of 300 µL. The solutions were incubated at 25 °C and 70 °C with orbital shaking at 40 rpm for 5 h. AuNP formation was assessed by measuring the SPR within the UV–Vis range (450–700 nm) using a POLARstar Omega microtitre plate reader (BMG Labtech, Germany). AuNP synthesis was scaled up to 2 mL following the optimum conditions.

Majoumouo M.S., Sharma J.R., Sibuyi N.R., Tincho M.B., Boyom F.F, & Meyer M. (2020). Synthesis of Biogenic Gold Nanoparticles from Terminalia mantaly Extracts and the Evaluation of Their In Vitro Cytotoxic Effects in Cancer Cells. Molecules, 25(19), 4469.

+ Open protocol

+ Expand

Synthesis and Characterization of Gold(III) Complexes

Check if the same lab product or an alternative is used in the 5 most similar protocols

Sodium tetrachloroaurate(III) dihydrate, Sodium dimethyldithiocarbamate monohydrate, sodium diethyldithiocarbamate trihydarte, sodium dibenzyldithiocarbamate hydrate, 2,2′-Bipyridine, 5,5′-dimethyl-2,2′-Bipyridine and 6,6′-dimethyl-2,2′-Bipyridine were purchased from Sigma-Aldrich Co. St. Louis, Missouri United States. All solvents including ethanol, dichloromethane were purchased from Merck Darmstadt, Germany and used without further purification. All reactions were carried out under ambient conditions.
Elemental analyses of gold(III) complexes (compounds 1–9) were performed on Perkin Elmer Series 11 (CHNS/O), Analyzer 2400. The solid state FTIR spectra of free ligands and their corresponding gold(I) complexes were recorded on a Perkin–Elmer FTIR 180 spectrophotometer or NICOLET 6700 FTIR using Potassium bromide (KBr) pellets over the range 4000–400 cm-1. 1H and 13C NMR spectra were recorded on a LAMBDA 500 spectrophotometer operating at 500.01, 125.65 and 200.0 MHz respectively, corresponding to a magnetic field of 11.74 T. Tetramethylsilane (TMS) was used as an internal standard for 1H and 13C. The 13C NMR spectra were obtained with 1H broadband decoupling, and the spectral conditions were: 32 k data points, 0.967 s acquisition time, 1.00 s pulse delay and 45 pulse angle.

Altaf M., Monim-ul-Mehboob M., Kawde A.N., Corona G., Larcher R., Ogasawara M., Casagrande N., Celegato M., Borghese C., Siddik Z.H., Aldinucci D, & Isab A.A. (2016). New bipyridine gold(III) dithiocarbamate-containing complexes exerted a potent anticancer activity against cisplatin-resistant cancer cells independent of p53 status. Oncotarget, 8(1), 490-505.

+ Open protocol

+ Expand

Green Synthesis of Gold Nanoparticles

Check if the same lab product or an alternative is used in the 5 most similar protocols

Sodium tetrachloroaurate (III) dihydrate (NaAuCl₄:2H₂O; 99%) was purchased from Sigma-Aldrich (St. Louis, MO, USA), silver nitrate (AgNO₃; 99.70%) was purchased from J.T. Baker (Mexico City, Mexico), and starch was purchased from CTR Scientific (Monterrey, NL, Mexico). The pH of the starting reaction solution was adjusted with sodium hydroxide (NaOH; 98.40%, CTR scientific, Monterrey, NL, Mexico). All of the experiments were carried out using deionized water and all the chemicals were used without further purification. Besides this, all of the glassware and stirring bars employed in all the synthetic steps were kept in an 11.11% hydrochloric acid (HCl; 37%, Sigma-Aldrich St. Louis, MO, USA) solution for 24 h, then in a potassium hydroxide/ethanol (KOH/EtOH; KOH ≥ 85%, Sigma-Aldrich St. Louis, MO, USA and EtOH reagent grade, CTR Scientific, Monterrey, NL, Mexico) solution during the same amount of time, and were finally rinsed with enough water prior to their use.

Nieto-Argüello A., Medina-Cruz D., Pérez-Ramírez Y.S., Pérez-García S.A., Velasco-Soto M.A., Jafari Z., De Leon I., González M.U., Huttel Y., Martínez L., Mayoral Á., Webster T.J., García-Martín J.M, & Cholula-Díaz J.L. (2022). Composition-Dependent Cytotoxic and Antibacterial Activity of Biopolymer-Capped Ag/Au Bimetallic Nanoparticles against Melanoma and Multidrug-Resistant Pathogens. Nanomaterials, 12(5), 779.

+ Open protocol

+ Expand

Synthesis and Characterization of Gold Nanoparticles

Check if the same lab product or an alternative is used in the 5 most similar protocols

All solvents used for extraction and column chromatography were general-purpose reagents. Methanol (AR), hexane, dichloromethane, m ethanol (HPLC grade), ethanol, ethyl acetate, sodium tetrachloroaurate (III) dihydrate (NaAuCl₄·2H₂O, 99.99%), and glycine (Gly) were purchased from Sigma-Aldrich (Cape Town, South Africa). Polyethylene glycol (PEG), cysteine (Cys), Dulbecco’s Modified Eagle (DMEM), and bovine serum albumin (BSA) from Miles Laboratories (Pittsburgh, PA, USA), and N-acetyl-L-cysteine from Boehringer Mannheim GmbH (Mannheim, Germany). Polystyrene 96-well microtiter plates were obtained from Greiner Bio-one GmbH (Frickenhausen, BY, Germany). Silica gel 60 (0.063–0.200 mm) and Sephadex (LH-20) were supplied by Merck (Darmstadt, Germany). The murine macrophage cell line, RAW 264.7, was obtained from the American Type Culture Collection (ATCC TIB-71, Manassas, VA, USA).

Eltahir A.O., Lategan K.L., David O.M., Pool E.J., Luckay R.C, & Hussein A.A. (2024). Green Synthesis of Gold Nanoparticles Using Liquiritin and Other Phenolics from Glycyrrhiza glabra and Their Anti-Inflammatory Activity. Journal of Functional Biomaterials, 15(4), 95.

+ Open protocol

+ Expand

Murine Osteoclastogenesis Protocol

Check if the same lab product or an alternative is used in the 5 most similar protocols

Fetal bovine serum (FBS), penicillin, streptomycin, and α-modified Eagle’s medium (α-MEM) were obtained from Gibco BRL (Gaithersburg, USA). Recombinant murine soluble RANKL and macrophage colony-stimulating factor (M-CSF) were purchased from Peprotech (London, UK). EGCG (98%) for cell, (Escherichia coli serotype 055: B5) LPS, sodium tetrachloroaurate (III) dihydrate (99%), FITC-labeled phalloidin and 4′,6-diamidino-2-phenylindole (DAPI), human serum albumins (HSA), were purchased from Sigma-Aldrich Co. (St Louis, MO, USA). EGCG for mice was obtained from Aladdin® (Shanghai, China). Primary antibodies against total JNK, phosphorylated JNK, ERK1, phosphorylated ERK1, p38, and phosphorylated p38 were purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA). BABL/c mice (male; 18–20 g body weight; 5 weeks of age) were purchased from the Experimental Animal Center of Hubei Province, Wuhan, China. All mice were housed under specific pathogen-free conditions. All procedures involving animals were approved by the Institutional Animal Care and Use Committee of Wuhan University (China).

Zhu S., Zhu L., Yu J., Wang Y, & Peng B. (2019). Anti-osteoclastogenic effect of epigallocatechin gallate-functionalized gold nanoparticles in vitro and in vivo. International Journal of Nanomedicine, 14, 5017-5032.

+ Open protocol

+ Expand

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Revolutionizing how scientists
search and build protocols!