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Contour next glucose monitor

Manufactured by Bayer

The Bayer Contour Next glucose monitor is a device designed to measure blood glucose levels. It provides users with a digital readout of their current glucose level.

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6 protocols using contour next glucose monitor

1

Streptozotocin-Induced Diabetes in Rats

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Male Sprague Dawley rats (Charles River) were used for experiments. Animal studies were performed in accordance with the guidelines for the care and use of laboratory animals; all protocols were approved by the Stanford Institutional Animal Care and Use Committee (Protocol #32873). The protocol used for diabetes induction using streptozotocin (STZ) was adapted from the protocol by Kenneth K. Wu and Youming Huan and was performed as previously reported.21 –22 (link), 26 –27 Briefly, Male Sprague Dawley rats 160–230 g (8–10 weeks) were weighed and fasted in the morning 6–8 hours prior to treatment with STZ (MedChemExpress). STZ was protected from light and diluted to 10 mg/mL in the sodium citrate buffer immediately before injection. STZ solution was injected intraperitoneally at 65mg/kg into each rat. Rats were provided with water containing 10% sucrose for 24 hours after injection with STZ and were given subcutaneous saline injections daily to prevent dehydration. Rat blood glucose levels were tested for hyperglycemia daily after the STZ treatment via tail vein blood collection using a handheld Bayer Contour Next glucose monitor (Bayer). Diabetes was defined as having three consecutive blood glucose measurements >400 mg/dL in non-fasted rats.
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2

Streptozotocin-Induced Diabetes in Rats

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Male Sprague Dawley rats (Charles River) were used for experiments. Animal studies were performed in accordance with the guidelines for the care and use of laboratory animals; all protocols were approved by the Stanford Institutional Animal Care and Use Committee. The protocol used for STZ induction adapted from the protocol by Kenneth K. Wu and Youming Huan.[51 ] Briefly, Male Sprague Dawley rats 160-230g (8-10 weeks) were weighed and fasted 6-8 hours prior to treatment with STZ. STZ was diluted to 10mg/mL in the sodium citrate buffer immediately before injection. STZ solution was injected intraperitoneally at 65mg/kg into each rat. Rats were provided with water containing 10% sucrose for 24 hours after injection with STZ. Rat blood glucose levels were tested for hyperglycemia daily after the STZ treatment via tail vein blood collection using a handheld Bayer Contour Next glucose monitor (Bayer). Diabetes was defined as having 3 consecutive blood glucose measurements >400 mg/dL in non-fasted rats.
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3

Streptozotocin Induced Diabetes in Rats

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Male Sprague Dawley rats (Charles River) were used for experiments. Animal studies were performed in accordance with the guidelines for the care and use of laboratory animals; all protocols were approved by the Stanford Institutional Animal Care and Use Committee (Protocol #32 873). The protocol used for streptozotocin (STZ) induction was adapted from the protocol by Kenneth K. Wu and Youming Huan and has been previously reported.[8, 12, 13, 21] Briefly, Male Sprague Dawley rats 160–230 g (8–10 weeks) were weighed and fasted in the morning 6–8 h prior to treatment with STZ. STZ was diluted to 10 mg mL−1 in the sodium citrate buffer immediately before injection. STZ solution was injected intraperitoneally at 65 mg kg−1 into each rat. Rats were provided with water containing 10% sucrose for 24 h after injection with STZ. Rat blood glucose levels were tested for hyperglycemia daily after the STZ treatment via tail vein blood collection using a handheld Bayer Contour Next glucose monitor (Bayer). Diabetes was defined as having three consecutive blood glucose measurements >400 mg dL−1 in non‐fasted rats.
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4

Streptozotocin-Induced Diabetes in Rats

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Male Sprague Dawley rats (Charles River) were used for experiments. Animal studies were performed in accordance with the guidelines for the care and use of laboratory animals; all protocols were approved by the Stanford Institutional Animal Care and Use Committee. The protocol used for STZ induction adapted from the protocol by Kenneth K. Wu and Youming Huan.[51 ] Briefly, Male Sprague Dawley rats 160-230g (8-10 weeks) were weighed and fasted 6-8 hours prior to treatment with STZ. STZ was diluted to 10mg/mL in the sodium citrate buffer immediately before injection. STZ solution was injected intraperitoneally at 65mg/kg into each rat. Rats were provided with water containing 10% sucrose for 24 hours after injection with STZ. Rat blood glucose levels were tested for hyperglycemia daily after the STZ treatment via tail vein blood collection using a handheld Bayer Contour Next glucose monitor (Bayer). Diabetes was defined as having 3 consecutive blood glucose measurements >400 mg/dL in non-fasted rats.
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5

Streptozotocin-Induced Diabetes in Rats

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Animal studies were performed in accordance with the Guidelines for the Care and Use of Laboratory Animals and the Animal Welfare Act Regulations; all protocols were approved by the Stanford Institutional Animal Care and Use Committee. The protocol used for STZ induction was adapted from the protocol by Kenneth K. Wu and Youming Huan40 . Briefly, male Sprague Dawley rats (Charles River Laboratory) of 200–300g (8–10 weeks) were weighed and fasted in the morning prior to treatment in the afternoon with STZ (6–8 hours). STZ was kept protected from light; immediately before administration, individual doses were diluted to 10 mg/mL in sodium citrate buffer. STZ solution was vortexed and administered intra-peritoneally to each rat at a dose of 65 mg/kg. Water containing 10% sucrose was given to rats for 24 hours after injection with STZ to prevent hypoglycemia. Rat blood glucose levels were tested for hyperglycemia daily after the STZ treatment via tail vein blood collection using a handheld Bayer Contour Next glucose monitor. Diabetes was defined as three consecutive blood glucose measurements >400 mg/dL in non-fasted rats.
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6

Streptozotocin-Induced Diabetes in Rats

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Animal studies were performed in accordance with the Guidelines for the Care and Use of Laboratory Animals and the Animal Welfare Act Regulations; all protocols were approved by the Stanford Institutional Animal Care and Use Committee. The protocol used for STZ induction was adapted from the protocol by Kenneth K. Wu and Youming Huan40 . Briefly, male Sprague Dawley rats (Charles River Laboratory) of 200–300g (8–10 weeks) were weighed and fasted in the morning prior to treatment in the afternoon with STZ (6–8 hours). STZ was kept protected from light; immediately before administration, individual doses were diluted to 10 mg/mL in sodium citrate buffer. STZ solution was vortexed and administered intra-peritoneally to each rat at a dose of 65 mg/kg. Water containing 10% sucrose was given to rats for 24 hours after injection with STZ to prevent hypoglycemia. Rat blood glucose levels were tested for hyperglycemia daily after the STZ treatment via tail vein blood collection using a handheld Bayer Contour Next glucose monitor. Diabetes was defined as three consecutive blood glucose measurements >400 mg/dL in non-fasted rats.
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