All patients underwent [18F]FDG-PET scans performed with PET cameras manufactured by GE Healthcare medical systems (GE Healthcare, Chicago, IL): GE Discovery PET/CT 690 (PD cohort: PD-LDR and PD-HDR, 256×256 matrix with a voxel size of 1.95 mm) and STE scanner (DLB, MSA and iRBD, 128×128 matrix with a pixel size of 1.95 mm). The [18F]FDG PET scans of 112 HC subjects were obtained using either a GE Discovery ST, GE Discovery STE, Siemens Biograph Hi-rez or Siemens ECAT EXACT HR + PET scanner (see (Caminiti et al., 2021 (link), Presotto et al., 2017 (link))). The [18F]FDG-PET acquisition procedures fulfilled the European Association of Nuclear Medicine guidelines (Varrone et al., 2009 (link)). Before radiopharmaceutical injection, subjects fasted for at least 6 h to ensure that the measured blood glucose level was <120 mg/dL. Subjects underwent a 3D PET scan (time interval between injection and scan start ranged from 30 to 45 min; scan duration ranged from 10 to 15 min) after the injection of [18F]FDG (185–250 MBq: usually, 5–8 mCi via a venous cannula). Reconstruction of all images was performed using an ordered subset-expectation maximisation algorithm (OSEM, 28 subsets, 2 iterations, 2-mm post-filter). For all clinical groups, CT scans were used for attenuation correction.
Ge discovery st
Manufactured by Siemens
The GE Discovery ST is a medical imaging system designed for computed tomography (CT) scanning. It provides high-quality imaging capabilities for diagnostic purposes. The core function of the GE Discovery ST is to capture detailed cross-sectional images of the body's internal structures, which can aid in the diagnosis and treatment of various medical conditions.
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Lab products found in correlation
Ge discovery pet ct 690, by GE Healthcare (1 mentions)
Biograph hi rez, by Siemens (1 mentions)
Ecat exact hr, by Siemens (1 mentions)
Ge discovery st, by GE Healthcare (1 mentions)
Ge discovery ls, by GE Healthcare (1 mentions)
Ge discovery ste, by GE Healthcare (1 mentions)
Somatom definition as, by Siemens (1 mentions)
2 protocols using ge discovery st
1
FDG-PET Imaging in Neurodegenerative Disorders
2
PET/CT Imaging Protocol for Cancer Staging
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PET/CT imaging was performed at diagnosis or staging and at treatment simulation. No restrictions were placed on the PET/CT system used. Staging imaging was performed on GE Discovery LS, GE Discovery ST, GE Discovery STE (GE Medical Systems, Milwaukee, WI), Philips Gemini TrueFlight (Philips Healthcare, Andover, MA), Siemens BioGraph HiRes Model 1080, and Siemens Biograph TruePoint Model 1093 (Siemens, Erlangen, Germany) scanners. Before 2012, simulation scans were performed on a GE Discovery ST platform, and after 2012 a Siemens Somatom Definition AS platform was used. The PET/CT protocol has been previously described11 (link) and consists of 8-hour fasting with blood glucose less than 160 mg/dL before injection of 10 to 18 mCi FDG, 45 to 60 minutes of tracer uptake time, and PET/CT acquisition with helical CT for attenuation correction.
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