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Premier mri scanner

Manufactured by GE Healthcare

The Premier MRI Scanner is a magnetic resonance imaging (MRI) system designed and manufactured by GE Healthcare. It is a diagnostic imaging device used to create high-quality images of the body's internal structures, such as organs, tissues, and bones. The Premier MRI Scanner utilizes powerful magnetic fields and radio waves to generate these detailed images, which can assist healthcare professionals in the diagnosis and monitoring of various medical conditions.

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4 protocols using premier mri scanner

1

Resting-State fMRI Acquisition Protocol

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The MRI studies were conducted at the University of Iowa Magnetic Resonance Research Facility (MRRF) on a 3T General Electric (GE) Discovery MR750W using a 32-channel head coil which was upgraded to a 3T GE Premier MRI Scanner with a 48-channel head coil. The same imaging protocol was used across scanner configurations. A reference T1-weighted anatomical brain image was collected via a coronal fast spoiled grass sequence (TI=450ms, TE=2.0ms, TR=5.2ms, Flip Angle=12°, Matrix=256×256×220, Field of View=256×256×220mm, Bandwidth = 488 Hz/pixel) for co-registration of all functional images. Resting state functional images were acquired using an echo-planar gradient-echo sequence with a voxel size of 3.4×3.4×4mm acquired in an ascending axial slice order and no gap between slices (TE=30ms, TR=2000ms, Flip Angle = 80°, Field of View =220×220mm, Matrix=64×64×35, Bandwidth= 7812Hz/pixel; 300 volumes for a total scan time of 600sec). All participants were instructed to attend their eyes on a fixation cross, relax, and remain awake during the resting state scan.
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2

Quantitative Thymic Fat Imaging

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All imaging scans were performed on the same 3T GE Premier MRI scanner at the Lucas Center for Imaging at Stanford University. Standardized methods for quantitatively determining thymic fat content have not been previously described, so we employed a computational methodology that has previously been applied to the analysis of bone marrow fat content (Hu, Nayak, & Goran, 2011). These methods for quantifying fat have been shown to be more accurate than standard histopathological assessment by biopsy (Fischer et al., 2012) and provide the thymic fat fraction (TFF) as a number from 0% to 100%. TFF was determined in three replicate central thymic regions at each tested time point and was used to compute the thymic fat‐free fraction (TFFF) as 100% ‐ TFF. The same methods were also applied to determine the sternal bone marrow fat‐free fraction (BMFFF). For more details, see Appendix S2.
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3

Brain Imaging of Cleft Palate Cohorts

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The first 47 participants (20 uAR, 11uIR, 16 iCL/P) were scanned using a 3.0 Tesla Siemens Trio MR scanner. Halfway through recruitment, the scanner was replaced with a 3.0 Tesla GE Premier MRI Scanner. The final 32 participants completed scanning on this scanner. Both scanners used a 12-channel head coil. The COMBAT harmonization method was applied to adjust for scanner-induced variation.43 (link),44 (link)
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4

Resting-State fMRI Acquisition Protocol

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The MRI studies were conducted at the University of Iowa Magnetic Resonance Research Facility (MRRF) on a 3 T General Electric (GE) Discovery MR750W using a 32-channel head coil which was upgraded to a 3 T GE Premier MRI Scanner with a 48-channel head coil. The same imaging protocol was used across scanner configurations. A reference T1-weighted anatomical brain image was collected via a coronal fast spoiled grass sequence (TI = 450 ms, TE = 2.0 ms, TR = 5.2 ms, Flip Angle = 12°, Matrix = 256x256x220, Field of View = 256 × 256 × 220mm, Bandwidth = 488 Hz/pixel) for co-registration of all functional images. Resting state functional images were acquired using an echo-planar gradient-echo sequence with a voxel size of 3.4 × 3.4 × 4mm acquired in an ascending axial slice order and no gap between slices (TE = 30 ms, TR = 2,000 ms, Flip Angle = 80°, Field of View =220x220mm, Matrix = 64 × 64 × 35, Bandwidth = 7,812 Hz/pixel; 300 volumes for a total scan time of 600 s). All participants were instructed to attend their eyes on a fixation cross, relax, and remain awake during the resting state scan.
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