The correlation between methylation β values and age was evaluated using Pearson’s correlation coefficient test. Differences in methylation β values were assessed for statistical significance by two-way analysis of variance (ANOVA) to compare the disc degeneration groups (ED and AD) and gender. All the statistical analyses were performed using IBM Statistical Package for Social Sciences Software (SPSS) Statistics (IBM Japan, Tokyo). The accepted level of significance was p<0.05.
Statistical package for social sciences software spss statistics
Manufactured by IBM
Sourced in Japan
SPSS Statistics is a software package used for interactive, or batched, statistical analysis. It is capable of handling a variety of data formats and can perform data manipulation, analysis, and presentation of results.
Automatically generated - may contain errors
Lab products found in correlation
4 protocols using statistical package for social sciences software spss statistics
1
Correlation of Methylation and Age
2
Comparative Analysis of Cartilage Imaging
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Differences in %DHI, 3D-DHI, and MRI T2-values were assessed for statistical significance by two-way repeated-measures analysis of variance (ANOVA) followed by the Bonferroni or Tukey’s Honest Significant Difference (HSD) post hoc test. Histological grading scores were assessed by the Kruskal-Wallis test for inter-group comparisons and the Friedman test for temporal changes. All data are expressed as mean ± standard deviation (SD). All the statistical analyses were performed using IBM Statistical Package for Social Sciences Software (SPSS) Statistics (IBM Japan, Tokyo). The accepted level of significance was P < 0.05.
3
Vertebral Biomechanics and Histology
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Biomechanical and histological data were statistically evaluated using a two-way analysis of variance (ANOVA) to evaluate differences between the groups and post-surgery period, and by the unpaired t-test to evaluate differences between the groups at each time point and between the time points of each group. The ratio of PS length excluding PS breach compared to the total PS length within the vertebra of the control and bioactive PSs was averaged and statistically analyzed using the Mann-Whitney U test. The correlation between this ratio and biomechanical data was statistically evaluated using the Spearman’s rank-order correlation test. All data are expressed as mean ± standard deviation (SD). All the statistical analyses were performed using IBM Statistical Package for Social Sciences Software (SPSS) Statistics (IBM Japan, Tokyo).
4
Evaluating IVD Degeneration via MRI and Histology
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Differences in %DHI and MRI T2-values were assessed for statistical significance by two-way repeated measures analysis of variance (ANOVA) to compare the IVD levels with time points of examination, followed by the Bonferroni post hoc test. Sample size was determined with a power analysis for an alpha of 0.05 and power of 0.80 using G*POWER3 [21 (link)] with a sample size of 5 animals at each time point. Histological grading scores were assessed by the Kruskal-Wallis test for inter-group comparisons and the Friedman test for temporal changes. The correlation between MRI T2-values and histological grading scores was evaluated using Spearman’s rank-order correlation test. The % of immuno-positive cells was evaluated by two-way ANOVA to compare IVD levels and disc area, followed by the Bonferroni post hoc test. All data were expressed as mean ± standard deviation (SD). All the statistical analyses were performed using IBM Statistical Package for Social Sciences Software (SPSS) Statistics (IBM Japan, Tokyo). The accepted level of significance was p < 0.05.
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