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Ammonium diethyldithiocarbamate

Manufactured by Merck Group
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Ammonium diethyldithiocarbamate is a chemical compound used in analytical laboratory applications. It functions as a complexing agent, facilitating the analysis and detection of various metal ions through spectrophotometric and other analytical techniques.

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Lab products found in correlation

Ammonium tetrathiomolybdate, by Merck Group (1 mentions) Disulfiram, by Merck Group (1 mentions) Z vad fmk, by InvivoGen (1 mentions) Sp600125, by InvivoGen (1 mentions) N acetyl l cysteine, by Merck Group (1 mentions) Paclitaxel, by Thermo Fisher Scientific (1 mentions) Cisplatin, by Thermo Fisher Scientific (1 mentions) Cis diammineplatinum 2 dichloride cisplatin, by Merck Group (1 mentions) Acetonitrile and methanol, by Thermo Fisher Scientific (1 mentions) Ammonium acetate, by Merck Group (1 mentions) Formic acid, by Merck Group (1 mentions) Acetic acid, by Merck Group (1 mentions)

2 protocols using ammonium diethyldithiocarbamate

1

Modulation of Cellular Signaling Pathways

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Stock solutions were prepared in dimethyl sulfoxide (Applichem): MEK1/2 inhibitor trametinib (1 mM; biomol #1187431), disulfiram (1 mM; Sigma Aldrich #97-77-8), ammonium diethyldithiocarbamate (1 mM; Sigma Aldrich #359548), ammonium tetrathiomolybdate (10 mM; Sigma Aldrich #15060), pan-caspase inhibitor Z-VAD-FMK (20 µM; InvivoGen #tlrl-vad), and JUN N-terminal kinase inhibitor SP600125 (100 mM, InvivoGen #tlrl-sp60). Stock solutions were prepared in aqueous buffer: copper (II) D-gluconate (1 mM, Sigma Aldrich #344419) in PBS and N-acetyl-L-cysteine (10 mM; Sigma Aldrich #A7250) in RPMI medium.
Meraz-Torres F., Niessner H., Plöger S., Riel S., Schörg B., Casadei N., Kneilling M., Schaller M., Flatz L., Macek B., Eigentler T., Rieß O., Garbe C., Amaral T, & Sinnberg T. (2024). Augmenting MEK inhibitor efficacy in BRAF wild-type melanoma: synergistic effects of disulfiram combination therapy. Journal of Experimental & Clinical Cancer Research : CR, 43, 30.
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2

Analytical Techniques for Paclitaxel and Cisplatin

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We purchased cis-diammineplatinum (II) dichloride (cisplatin) from Sigma-Aldrich (St. Louis, MO, USA), and paclitaxel was donated from Samyang Biopharmaceuticals Corp. (Seongnam, Korea). For analyzing serum and tissue concentrations of paclitaxel and cisplatin, we purchased acetonitrile and methanol from Fisher Scientific (Waltham, MA, USA) and formic acid, acetic acid, ammonium diethyldithiocarbamate, and ammonium acetate from Sigma-Aldrich.
Park S.J., Lee E.J., Seol A., Park S., Ham J., Yim G.W., Shim S.H., Lim W., Chang S.J., Song G., Park J.W, & Kim H.S. (2022). Rotational intraperitoneal pressurized aerosol chemotherapy with paclitaxel and cisplatin: pharmacokinetics, tissue concentrations, and toxicities in a pig model. Journal of Gynecologic Oncology, 33(5), e56.
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