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Brij s10

Manufactured by Merck Group
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Brij S10 is a non-ionic surfactant that is commonly used in various laboratory applications. It is a polyoxyethylene ether-based compound with the chemical formula C12H25(OCH2CH2)10OH. Brij S10 is a versatile and widely-used reagent in the field of biochemistry, cell biology, and analytical chemistry.

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Lab products found in correlation

Brij s100, by Merck Group (3 mentions) Glycerin, by Merck Group (2 mentions) Brij s20, by Merck Group (2 mentions) Brij s2, by Merck Group (2 mentions) Dialysis bag, by Yuanye Bio-Technology (1 mentions) Poloxamer 188, by Merck Group (1 mentions) Span 85, by Merck Group (1 mentions) Human serum albumin (hsa), by Tokyo Chemical Industry (1 mentions) Tween 80, by Merck Group (1 mentions) Ultrafiltration tube, by Merck Group (1 mentions) Ethyl acetate, by RCI Labscan (1 mentions) Cetyl palmitate, by Merck Group (1 mentions) Dimethyl sulfoxide (dmso), by RCI Labscan (1 mentions) Glyceryl monostearate, by Merck Group (1 mentions) Propylene glycol, by Merck Group (1 mentions) Polyethylene glycol 400, by Merck Group (1 mentions) N hexane, by RCI Labscan (1 mentions) Ethanol, by RCI Labscan (1 mentions) Stearic acid, by Merck Group (1 mentions) Bovine serum albumin (bsa), by Merck Group (1 mentions)

5 protocols using brij s10

1

Synthesis and Characterization of Mannose-Targeted Liposomes

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Glyceryl monostearate and stearic acid were purchased from Beijing Fengli Jingqiu Commerce and Trade Co., Ltd (Beijing, China). Glyceryl behenate was purchased from Guangzhou Tianrun Pharmaceutical Co., Ltd (Guangzhou, China). Egg yolk lecithin and soybean lecithin were purchased from Shanghai Tywei Co., Ltd (Shanghai, China). Poloxamer 188, Span 85, Tween 80, glycerin, and Brij S10 were obtained from Sigma-Aldrich (ST. Louis, USA). MT and FBS was purchased from Innochem Technology Co., Ltd (Beijing, China). P-nitrophenyl-a-D-mannopyranoside, N-succinimidyl-S-acetylthioacetate (SATA), and phosphatidylethanolamine-PEG-maleimide (DSPE-PEG-MAL) were bought from Shanghai Yiyan Biological Technology Co., Ltd (Shanghai, China). Human serum albumin was purchased from Tokyo Chemical Industry (Shanghai) Development Co., Ltd (Shanghai, China). Phosphorus oxychloride, palladium 10% on carbon, and thiophosgen were bought from Energy Chemical Technology (Shanghai) Co., Ltd (Shanghai, China). Dialysis bags (2500 kDa cutoff) were purchased from Shanghai Yuanye Biological Technology Co., Ltd (Shanghai, China). Ultrafiltration tubes (3 kDa cutoff) were bought from Merck Millipore (Germany). Acetonitrile, methanol, ethanol, and ethyl acetate were of HPLC grade, and other reagents were of analytical grade.
Tan X., Hao Y., Ma N., Yang Y., Jin W., Meng Y., Zhou C., Zheng W, & Zhang Y. (2023). M6P-modified solid lipid nanoparticles loaded with matrine for the treatment of fibrotic liver. Drug Delivery, 30(1), 2219432.
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2

Development of Nanoemulsion Formulations

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Rosmarinic acid (RA), polysorbate 20 (Tween 20®), polysorbate 80 (Tween 80®), steareth-10 (Brij S10®), polyoxyethylene mono (octylphenyl) ether (Triton X-114®), decyl glucoside (Plantacare 2000®), polyethylene glycol 400 (PEG-400), propylene glycol, glycerin, cholesterol, stearic acid, glyceryl monostearate, cetyl palmitate, and bovine serum albumin (BSA) were purchased from Sigma-Aldrich (St. Louis, MO, USA). Tea seed (Camellia oleifera Abel.) oil, avocado (Persea americana Mill.) oil, and almond (Prunus dulcis Mill.) oil were cosmetic grade purchased from Namsiang (Chiang Mai, Thailand). HPLC grade acetonitrile was purchased from Merck (Darmstadt, Germany). Ethanol, ethyl acetate, n-hexane, and dimethyl sulfoxide (DMSO) were analytical grade purchased from Labscan (Dublin, Ireland).
Chaiyana W., Anuchapreeda S., Somwongin S., Marsup P., Lee K.H., Lin W.C, & Lue S.C. (2020). Dermal Delivery Enhancement of Natural Anti-Ageing Compounds from Ocimum sanctum Linn. Extract by Nanostructured Lipid Carriers. Pharmaceutics, 12(4), 309.
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3

Synthesis and Characterization of Dodecyl Prodrugs

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Dodecyl prodrug/drug analogue was used as synthesised by previous publication. Brij S10, Brij S20, Brij S100, tetrahydrofuran and deuterated solvents (CDCl3 and D2O) were all purchased from Sigma Aldrich and used as received apart from CDCl3 where 0.1% tetramethylsilane was added. Lipoid S100 was purchased from Lipoid and used as received. Tricaprin was purchased from Tokyo chemical industry and used as received. Dynasan 114 (trimyrisitn) and Dynasan 118 (tristearin) was kindly gifted from IOI Oleochemical, Hamburg. Lamivudine was purchased from Top Well Medipharma Group.
Hogarth C., Arnold K., Wright S., Elkateb H., Rannard S, & McDonald T.O. (2023). Navigating the challenges of lipid nanoparticle formulation: the role of unpegylated lipid surfactants in enhancing drug loading and stability. Nanoscale Advances, 6(2), 669-679.
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4

Evaluation of P-glycoprotein Modulators

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BBR was purchased from Oddfoni Biological Technology Company (Nanjing, China). Verapamil, cyclosporin A (CsA), and Rhodamine123 were purchased from J&K Scientific Ltd. (Bei-jing, China). 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT), methanol, dimethyl sulphoxide (DMSO), and Brijs (Brij-L4, decaethylene glycol monododecyl ether [BD], Brij-L23, Brij-52 Brij-C10, Brij-58, Brij-93, Brij-O10, Brij-O20, Brij-S2, Brij-S10, Brij-S20, Brij-S100, D-α-Tocopherol polyethylene glycol 1000 succinate [TPGS]) were purchased from Sigma-Aldrich Co. (St. Louis, MO, USA). High-performance liquid chromatography (HPLC) grade acetonitrile was purchased from Merck Company (Darmstadt, Germany).
ATPlite luminescence ATP detection assay system was bought from Perkin Elmer (Waltham, MA, USA). Pgp-Glo assay system with human Pgp membrane was obtained from Promega (Madison, WI, USA). All materials for cell culture were obtained from Thermo Fisher Scientific (Waltham, MA, USA). Antibodies against Pgp and GAPDH, and anti-rabbit IgG were obtained from Cell Signaling Technology (Beverly, MA, USA).
Xiong W., Sang W., Linghu K.G., Zhong Z.F., Cheang W.S., Li J., Hu Y.J., Yu H, & Wang Y.T. (2018). Dual-functional Brij-S20-modified nanocrystal formulation enhances the intestinal transport and oral bioavailability of berberine. International Journal of Nanomedicine, 13, 3781-3793.
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5

Synthesis of Mesoporous Silica Nanoparticles

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Tetraethyl orthosilicate (TEOS, 98%), ethanol (EtOH, 99%), and aqueous ammonia (28%) were purchased from Sinopharm Chemical Reagent Co. Ltd. Di(ethylene glycol) ethyl ether acrylate (DEGEEA, 90%), Brij S2 (Mn: 358.6), Brij S10 (Mn: 711), Brij S100 (Mn: 4670), IGEPAL CO720 (Mn: 749), CO890 (Mn: 1982), and 2-hydroxy-2-methylpropiophenone (photoinitiator, 96%) were obtained from Sigma-Aldrich. All the chemicals were used as received without further purifications.
Yang D., Hu Y., Ma D., Ge J, & Huang S. (2022). Reconfigurable Mechanochromic Patterns into Chameleon-Inspired Photonic Papers. Research, 2022, 9838071.
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