Su dhl 4

293T/17, Namalwa (human Burkitt lymphoma cell), Karpas-299 (human anaplastic large cell lymphoma cells), Daudi (human Burkitt lymphoma cells), HL-60 (human myeloid leukemia cells), Su-DHL-4 (human diffuse large B-cell lymphoma cells), Kasumi-1 (human acute myeloid leukemia cells), HEL (human erythroleukemia leukemia cells), K562 (human chronic myeloid leukemia cells), THP1 (human monocyte leukemia cells) and Jurkat (human T lymphocytic leukemia cells) cell lines were purchased from the Shanghai Cell Bank, Chinese Academy of Sciences (Shanghai, China). The lentivirus packaging cell line 293T/17 was maintained in Dulbecco's modified Eagle's medium (DMEM; Hyclone; GE Healthcare Life Sciences, Logan, UT, USA). The remaining hematological tumor cells were cultured in Iscove's modified Dulbecco's medium (IMDM) or RPMI-1640 medium (Hyclone; GE Healthcare Life Sciences). Cell cultures were supplemented with 0.1 U/ml streptomycin, 0.1 U/µl penicillin and 10% fetal bovine serum (FBS; Gibco; Thermo Fisher Scientific, Inc., Waltham, MA, USA). The cells were cultured at 37°C in a humidified atmosphere of 5% CO₂.

Human normal B-cell immortalized cell line (HMy2.CIR), DLBCL cell line, germinal central B-cell (GCB)-like OCI-Ly19 and SU-DHL-4, and ABC-like OCI-LY10 and U2932 were purchased from Shanghai Cell Bank of the Chinese Academy of Sciences. HMy2.CIR was cultured in Iscove’s modified dulbecco’s medium (IMDM) (Gibco, Carlsbad, CA, USA) containing 10% fetal bovine serum (FBS), and 1% penicillin–streptomycin (P/S). U2932 and SU-DHL-4 were cultured in RPMI 1640 medium (Gibco) containing 10% FBS and 1% P/S. OCI-LY10 and OCI-Ly19 were cultured in IMDM (Gibco) containing 20% FBS and 1% P/S. All cells were maintained in a humid incubator with 5% CO₂ at 37°C.