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Erythromycin

Manufactured by Abbott

Erythromycin is a macrolide antibiotic used in laboratory settings. It is a naturally-derived compound produced by the bacterium Saccharopolyspora erythraea. Erythromycin functions as an antimicrobial agent by inhibiting bacterial protein synthesis.

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2 protocols using erythromycin

1

Comprehensive Evaluation of Pharmaceutical Compounds

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Remdesivir (RDV), GS704277, THC, CBD, CBN, hydroxychloroquine were purchased from Cayman Chemical (Ann Arbor, MI). Azithromycin was purchased from Pfizer Inc. (New York NY). Erythromycin, clarithromycin was purchased from Abbott Laboratories Inc. (Chicago, IL). Dexamethasone, trimethoprim, ivermectin ciprofloxacin, roxithromycin, vancomycin, aripiprazole, ziprasidone, and phenacetin were purchased from Sigma-Aldrich Inc. (St. Louis, MO). Phosphate buffered saline (PBS) was purchased from Thermo Fisher Scientific Inc. (Waltham, MA). All other chemicals and reagents were of the highest analytical grade and were commercially available.
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2

Characterization of S. aureus SrtA Mutant

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The S. aureus 8325–4 wild type (WT) strain and its isogenic srtA deletion mutant (srtA KO) were used in this study. The srtA mutant was generated by srtA:ermC allele transduction, as previously described [9 (link), 13 (link)]. The srtA KO mutant was selected and maintained on brain-heart infusion agar (BHA, BD (Becton Dickinson and Company)-Difco, Etten-Leur, The Netherlands) plates supplemented with 3 μg/ml erythromycin (Abbott Laboratories, North Chicago, Illinois, U.S.).
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