3t magnetic resonance scanner

Manufactured by Philips

Sourced in Netherlands

The 3T magnetic resonance scanner is a piece of lab equipment designed for high-resolution imaging. It generates a strong 3 Tesla magnetic field to produce detailed images of the internal structures of the human body. The scanner is a precision instrument used for diagnostic purposes in medical and research settings.

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Lab products found in correlation

3t scanner, by Philips (1 mentions) Ge 1.5t, by Philips (1 mentions) 1.5t system, by GE Healthcare (1 mentions)

Spelling variants of this product

3T scanner (120 citations) 3T whole body magnetic resonance scanner (2 citations)

5 protocols using 3t magnetic resonance scanner

fMRI Acquisition for Neuroimaging Studies

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The data were acquired from the Center for Biomedical Imaging Research of Tsinghua University. The fMRI scanning was performed using a 3 T magnetic resonance scanner (Philips, Netherlands) with a 32-channel frequency head coil. To restrict head movements, the participants' heads were fixed with plastic braces and foam pads during the entire experiment. To perform the functional imaging, we used an echo-planar sequence based on blood oxygenation level-dependent (BOLD) contrast with the following parameters: time (TR) = 2000 ms, echo time (TE) = 35 ms, flip angle (FA) = 90°, field of view (FOV) = 200 mm × 200 mm, 64 × 64 matrix, voxel size = 2.5 × 2.5 × 4 mm³, 30 slices, and 4 mm thickness. T2^∗-weighted function images parallel to the anterior commissure-posterior commissure (AC-PC) were obtained. To obtain structural images, high-resolution structural T1^∗-weighted anatomical scanning was performed using a 3D gradient-echo pulse sequence (TR = 7.65, TE = 3.73, flip = 90°, FOV = 230 mm × 230 mm, and voxel size = 0.96 mm × 0.96 mm × 1 mm).

Zhan J., Ren J., Sun P., Fan J., Liu C, & Luo J. (2018). The Neural Basis of Fear Promotes Anger and Sadness Counteracts Anger. Neural Plasticity, 2018, 3479059.

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Quantitative MRI of SPION-Loaded Nanoparticles

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According to the concentration of SPION concentration in the samples as 0.067 mM, 0.135 mM, 0.27 mM, 0.54 mM, and 1.08 mM, a series of FTY720@SPION/PFP/RGD-NBs in PBS solutions were prepared. The samples (1.5 mL per tube) were scanned using a 3T magnetic resonance scanner (Philips Achieva, Best, Netherlands) at room temperature. The MRI scan sequence includes T2WI and T2 mapping. The T2WI parameters are as follows: TR/TE = 2600 ms/100 ms; flip angle = 90°; NA (number of acquisitions) = 6; acquisition matrix = 384 × 305; FOV (field of view) = 80 mm × 80 mm; slice thickness = 2 mm; slice gap = 2 mm. T2 mapping used single-layer, multi-echo self-selected echo sequence scanning, and the parameters are as follows: TR = 1500 ms; TE = 0, 20, 40, …, 160 ms; NA = 3; acquisition matrix = 176 × 123 mm; FOV = 80 mm × 80 mm; slice thickness = 1.5 mm; slice gap = 1.5 mm. According to the scanned MRI T2 map, the transverse relaxation time T₂ of each SPION concentration was obtained, and linear fitting was performed to calculate the transverse relaxation rate R₂ of the SPION sample.

Guo X.M., Chen J.L., Zeng B.H., Lai J.C., Lin C.Y, & Lai M.Y. (2020). Ultrasound-mediated delivery of RGD-conjugated nanobubbles loaded with fingolimod and superparamagnetic iron oxide nanoparticles: targeting hepatocellular carcinoma and enhancing magnetic resonance imaging. RSC Advances, 10(64), 39348-39358.

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Multi-site Structural MRI Acquisition

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All structural MRIs were obtained on three different sites: a Philips 1.5T system at Guy's Hospital, a General Electric (GE) 1.5T at the Institute of Psychiatry, and a Philips 3T magnetic resonance scanner at Hammersmith Hospital. The T1-weighted structural MRIs were acquired using a magnetization-prepared rapid acquisition gradient-echo (MPRAGE) sequence. Scanning parameters for Philips 1.5T scanner were: TR = 9.8 ms, TE = 4.6 ms, flip angle = 8°; and for Philips 3T scanner were: TR = 9.6 ms, TE = 4.6 ms, flip angle = 8°. Scanning parameters for GE 1.5T scanner were not available.

Liu K., Yao S., Chen K., Zhang J., Yao L., Li K., Jin Z, & Guo X. (2017). Structural Brain Network Changes across the Adult Lifespan. Frontiers in Aging Neuroscience, 9, 275.

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Automated Quantification of White Matter Hyperintensities

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Participants who screened positive by TCD received a brain MRI assessment using a 3‐T magnetic resonance scanner (Philips, Achieva, Netherlands), including T1‐weighted images, T2‐weighted images, proton density images, T2 fluid‐attenuated inversion recovery images, and diffusion‐weighted imaging, as described previously (Sun et al., 2020 (link)). WMH was calculated by two trained investigators and a neuroradiologist blinded to clinical information using the lesion segmentation tool (LST) for the Statistical Parametric Mapping package (SPM) (Schmidt et al., 2019 (link)). WMH was defined as hyperintensities on proton density and T2‐weighted images, with no prominent hypointensity on T1‐weighted images. The volume of WMH was divided into four categories; patients with WMH volumes in the highest (4th) quartile were classified into the severe WMH group (≥4.20 ml). Figure 1 shows a flowchart of the WMH volume using LST auto‐calculation.

Wang X., Yin H., Ji X., Sang S., Shao S., Wang G., Lv M., Xue F., Du Y, & Sun Q. (2021). Association between homocysteine and white matter hyperintensities in rural‐dwelling Chinese people with asymptomatic intracranial arterial stenosis: A population‐based study. Brain and Behavior, 11(7), e02205.

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Resting-state fMRI in Cocaine Dependence

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Cocaine-dependent individuals completed scans during their final week of a 2- to 4-week residential treatment program. Participants completed fMRI scans during which they were instructed to lie as still as possible with their eyes open. Two control participants were excluded from all imaging analysis due to a technical error during acquisition of the resting data. Functional MRI acquisition was performed on a Philips 3T magnetic resonance scanner (Philips Medical Systems, Best, The Netherlands). BOLD fMRI data during the SST experiment were acquired using a single-shot echo-planar imaging sequence with 3.25 χ 3.25 mm² in-plane resolution, 36 slices (thickness/gap = 3/0 mm), field-of-view (FOV) 208 × 208 × 108 mm, matrix size 64 × 64 × 36, repetition time/echo time = 1,700/25 milliseconds, gradient-echo echo-planar imaging (EPI) with flip angle 70°, and 384 volumes over the duration of about 653 s. For spatial normalization purposes, high-resolution T1-weighted images were acquired with a spatial resolution of 1 × 1 × 1 mm³.

Sakoglu U., Mete M., Esquivel J., Rubia K., Briggs R, & Adinoff B. (2019). Classification of cocaine-dependent participants with dynamic functional connectivity from functional magnetic resonance imaging data. Journal of neuroscience research, 97(7), 790-803.

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