Prucka cardiolab ep system

Manufactured by GE Healthcare

Sourced in United States

The Prucka CardioLab EP system is a comprehensive electrophysiology (EP) laboratory system designed for the diagnosis and treatment of cardiac arrhythmias. The system provides advanced tools for recording, analyzing, and displaying cardiac electrical activity data.

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Lab products found in correlation

Navistar, by Johnson & Johnson (1 mentions) Navistar catheter, by Johnson & Johnson (1 mentions) Carto xp, by Johnson & Johnson (1 mentions)

4 protocols using prucka cardiolab ep system

Mapping Ventricular Tachycardia Substrates

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Twelve-lead ECGs of all induced ventricular tachycardia (VT) of patients with prior myocardial infarction who underwent radiofrequency catheter ablation (RFCA) for monomorphic VT at LUMC were reviewed. All patients provided informed consent and were treated according to the clinical protocol. Programmed electrical stimulation (PES) is routinely performed before RFCA to determine inducibility of the clinical/presumed clinical VT. All the patients underwent PES and ablation according to the standard clinical protocol, therefore no ethical approval was required. Ablation typically targets the substrate for scar-related reentry VT. After ablation PES is repeated to test for re-inducibility and evaluate morphology and cycle length of remaining VTs. The significance of non-clinical, fast VTs is unclear and these VTs are often not targeted by RFCA. PES consisted of three drive cycle lengths (600, 500 and 400 ms), one to three ventricular extrastimuli (≥200 ms) and burst pacing (CL ≥200 ms) from at least two right ventricular (RV) sites and one LV site. A positive endpoint for stimulation is the induction of any sustained monomorphic VT lasting 30 s or requiring termination. ECG and intracardiac electrograms (EG) during PES were displayed and recorded simultaneously on a 48-channel acquisition system (Prucka CardioLab EP system, GE Healthcare, USA) for off-line analysis.

Vandersickel N., Watanabe M., Tao Q., Fostier J., Zeppenfeld K, & Panfilov A.V. (2018). Dynamical anchoring of distant arrhythmia sources by fibrotic regions via restructuring of the activation pattern. PLoS Computational Biology, 14(12), e1006637.

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Intraprocedural Monitoring of Irreversible Electroporation

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Data were obtained in 30 patients who underwent PVI using single-pulse IRE during clinical studies which were approved by the Medical Research Ethics Committee at the University Medical Center Utrecht.^{2 (link)} During these studies, a custom 14-polar (2.5-mm electrodes, 3.5 mm spacing, with a variable hoop of 16–27 mm) circular IRE catheter was used to deliver IRE applications.^{2 (link),5} During the whole procedure, endocardial signals were recorded using a recording system (Prucka Cardiolab EP system, GE Healthcare). At the start of the procedure, the IRE catheter was moved freely in the LA for a period of at least 30 seconds while recording both bipolar electrograms and MEIS signals. MEIS values per electrode were recorded continuously but were not used to guide the ablation procedure.

Groen M.H., van Driel V.J., Neven K., van Wessel H., de Bakker J.M., Doevendans P.A., Wittkampf F.H., Loh P, & van Es R. (2022). Multielectrode Contact Measurement Can Improve Long-Term Outcome of Pulmonary Vein Isolation Using Circular Single-Pulse Electroporation Ablation. Circulation. Arrhythmia and Electrophysiology, 15(8), e010835.

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Electrophysiological Study and Catheter Ablation

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The patients underwent electrophysiological (EP) study and catheter ablation. Surface and intra-cardiac ECGs were digitally recorded and stored (PruckaCardioLab EP System, GE Healthcare, Waukesha, WI, USA). Non-fluoroscopic three-dimensional mapping was performed in each case either using the Carto (Biosense-Webster, Diamond Bar, CA, USA) or the Niobe II magnetic navigation system (Stereotaxis Inc., StLouis, MO, USA) integrated with CARTO-remote magnetic technology (RMT) system (Biosense Webster, Inc. 33 Technology Drive Irvine, CA, USA)^{[12 ]} at the operator's discretion.
The conventional EP leads were placed properly, and multiple electrode catheter was advanced into the heart and placed at the right atrium and ventricle, at the His bundle and within the coronary sinus. A routine EP study was carried out under local anesthesia. Sinus node recovery time (SNRT), Wenckebach block point (WP), AV conduction time, atrium-His bundle (AH), and His bundle-ventricle (HV) interval and their changes were recorded before and after ablation. Bipolar electrograms were recorded with a bandpass filter at 30 to 500 Hz using a 4-mm-tip mapping/ablation catheter (NaviStar, Biosense Webster, Diamond Bar, CA, USA).

Lu C.S., Guo C.J., Fang D.P., Hao P., He D.F, & Xu A.G. (2020). Initial experience with ablation of the innervation surrounding sinus and atrioventricular nodes to treat paroxysmal bradyarrhythmia. Chinese Medical Journal, 133(2), 134-140.

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Atrial Electrogram Recordings for AF Analysis

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Bipolar electrograms were sequentially obtained from multiple sites in the right and left atria (RA and LA) and stored on the Prucka CardioLab EP System (GE Healthcare, Waukesha, WI) at a sample rate of 977 Hz. The majority of the signals were collected with a Navistar catheter (Biosense Webster, Inc., Diamond Bar, CA, USA) but diagnostic catheters were used for coronary sinus recordings and were also used for multisite recordings in some patients. At least 15 seconds of electrograms were recorded at each site. Recording sites were documented using an electroanatomical mapping system (NavX, St. Jude Medical; or CartoXP, Biosense Webster). Electrograms were obtained from distributed RA (appendage, lateral wall, superior and inferior vena cava junctions, posterior wall, and septum) and LA (septum, roof, posterior wall, appendage, and the ostia of the four PVs) locations. In addition, we analyzed 36 electrograms from seven patients with typical atrial flutter recorded from multiple sites in the RA to compare recurrence analysis during AF with a non-fibrillatory arrhythmia where stable activation patterns were expected.

Ng J., Gordon D., Passman R.S., Knight B.P., Arora R, & Goldberger J.J. (2014). Electrogram Morphology Recurrence Patterns during Atrial Fibrillation. Heart rhythm : the official journal of the Heart Rhythm Society, 11(11), 2027-2034.

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