Avicel® PH is a microcrystalline cellulose product designed for use in pharmaceutical and nutritional applications. It is a purified, partially depolymerized cellulose prepared by treating alpha-cellulose, obtained as a pulp from natural sources, with mineral acids. Avicel® PH is a white, odorless, tasteless, crystalline powder that is insoluble in water, dilute acids, and most organic solvents.
Example 9
After crystallization, polymorph forms of Formula I compound, may be formulated by dry granulation using a roller compactor, followed by a tableting operation. Additional ingredients in the tablets may include microcrystalline cellulose (Avicel PH, FMC BioPolymer), lactose (FastFlo, Foremost Farms USA), sodium starch glycolate (EXPLOTAB, JRS Pharma), or magnesium stearate (Hyqual, Macron Fine Chemicals).
Example 9
After crystallization, polymorph forms of Formula I compound, may be formulated by dry granulation using a roller compactor, followed by a tableting operation. Additional ingredients in the tablets may include microcrystalline cellulose (Avicel® PH, FMC BioPolymer), lactose (FastFlo®, Foremost Farms USA), sodium starch glycolate (EXPLOTAB®, JRS Pharma), or magnesium stearate (Hyqual®, Macron Fine Chemicals).
Example 9
After crystallization, polymorph forms of Formula I compound, may be formulated by dry granulation using a roller compactor, followed by a tableting operation. Additional ingredients in the tablets may include microcrystalline cellulose (Avicel® PH, FMC BioPolymer), lactose (FastFlo®, Foremost Farms USA), sodium starch glycolate (EXPLOTAB®, JRS Pharma), or magnesium stearate (Hyqual®, Macron Fine Chemicals).
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