The chest CT and PET/CT scans were acquired using various protocols and scanners at our medical center across a ten-year time frame. The CT scanners used during the study years included GE Medical Systems (models: Optima-CT660, LightSpeed-VCT, LightSpeed-Ultra) and Siemens (models: Emotion and Emotion-Duo). The CT images were consistently reconstructed to encompass the entire lung field in a 512×512 pixel matrix. The in-plane pixel dimensions ranged from 0.55 to 0.81 mm, depending on participant body size. The image thickness ranged from 0.625 mm to 2.5 mm. The PET/CT scanners were manufactured by GE Medical Systems (model: Discovery ST), CPS (model: 1023), and Siemens (Emotion and Emotion-Duo). PET/CT scans were typically obtained from the head to the upper portion of the thigh on an integrated PET/CT scanner. The PET images had a matrix size of 128 × 128 with an in-plane resolution ranging from 4.1 mm to 5.5 mm. The image thickness of the PET images ranged from 2.5 mm to 3.38 mm.
Emotion duo
Manufactured by Siemens
Sourced in Germany
The Emotion Duo is a laboratory equipment designed for the measurement and analysis of emotional responses. It incorporates advanced sensor technology to capture physiological data associated with emotional states. The core function of the Emotion Duo is to provide accurate and reliable data collection for research and clinical applications.
Automatically generated - may contain errors
6 protocols using emotion duo
1
Multimodal Imaging Protocols for Lung Evaluation
2
Rando Phantom Dosimetry and Treatment Planning
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Commercially available RANDO phantom (The Phantom Laboratory, Salem, NY) is made from a skeletal structure and plastic tissue equivalent material.
This phantom is composed of 36 slices, with numbers ranging from 0 to 35. The thickness of 0 to 34 slices is 2.5 cm and the thickness of the pelvic base
(slice number 35) is about 9 cm. Most of the slices include holes to hold TLD chips for the purpose of in-phantom dosimetry [ 20 (link) ].
In the irradiation set-up, the RANDO phantom was positioned on the couch of a Siemens computed tomography machine (Siemens Somatom, Emotion Duo) in Reza Radiation Oncology
center (Mashhad, Iran). Computed tomography images with 0.5 cm slices were acquired from the RANDO phantom. Using the images, treatment planning was performed by a commercial
Prowess Panther treatment planning system (Prowess Inc., Concord, CA, USA) with designing a right anterior-oblique and right posterior-oblique fields.
A clinical oncologist in the aforementioned center performed treatment planning. The characteristics of this treatment planning are listed inTable 2 .
This phantom is composed of 36 slices, with numbers ranging from 0 to 35. The thickness of 0 to 34 slices is 2.5 cm and the thickness of the pelvic base
(slice number 35) is about 9 cm. Most of the slices include holes to hold TLD chips for the purpose of in-phantom dosimetry [ 20 (link) ].
In the irradiation set-up, the RANDO phantom was positioned on the couch of a Siemens computed tomography machine (Siemens Somatom, Emotion Duo) in Reza Radiation Oncology
center (Mashhad, Iran). Computed tomography images with 0.5 cm slices were acquired from the RANDO phantom. Using the images, treatment planning was performed by a commercial
Prowess Panther treatment planning system (Prowess Inc., Concord, CA, USA) with designing a right anterior-oblique and right posterior-oblique fields.
A clinical oncologist in the aforementioned center performed treatment planning. The characteristics of this treatment planning are listed in
3
Evaluating 18F-FLT PET/CT in Sarcoma
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Of the 46 18F-FLT PET/CT scans, 43 (93%) were performed on a Siemens Biograph 64 TruePoint PET/CT scanner and 3 (7%) on a Siemens Emotion Duo PET/CT scanner approximately 1 h after a median injected activity of 247.9 MBq (IQR, 229.4–255.3 MBq). Intravenous and oral contrast media were administered in 33 scans (72%) and 36 scans (78%), respectively.
Several SUV parameters were assessed on PET 1 and PET2: SUVmax, SUVpeak, SUVmean, and SUV for total-lesion FLT with a 40%, 50%, 60%, and 80% cutoff of SUVmax. Because SUVmax proved to be equal or superior to the other PET parameters, we selected SUVmax for further analyses. 18F-FLT PET/CT images were interpreted by 1 reader. The reader was aware of the sarcoma diagnosis but not of the treatment regimen or other clinical and outcome data.
Posttreatment pathology specimens were assessed by tumor necrosis or fibrosis and by Ki-67 and TK1 expression as described previously (8 (link)).
Several SUV parameters were assessed on PET 1 and PET2: SUVmax, SUVpeak, SUVmean, and SUV for total-lesion FLT with a 40%, 50%, 60%, and 80% cutoff of SUVmax. Because SUVmax proved to be equal or superior to the other PET parameters, we selected SUVmax for further analyses. 18F-FLT PET/CT images were interpreted by 1 reader. The reader was aware of the sarcoma diagnosis but not of the treatment regimen or other clinical and outcome data.
Posttreatment pathology specimens were assessed by tumor necrosis or fibrosis and by Ki-67 and TK1 expression as described previously (8 (link)).
4
CT-Guided Radiotherapy Planning and Monitoring
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All patients were moved into the CT simulation (Siemens Emotion Duo) gantry head first. The supine group was immobilized using a carbon fiber base plate (CIVCO Medical Solutions, Orange City, Iowa, USA) and thermoplastic mask (Orfit, Wijnegem, Belgium). The prone group was immobilized using the belly board device (CIVCO Medical Solutions, Orange City, Iowa, USA). The CT simulation scans used a 5-mm slice thickness and spacing, ranging from the third lumbar vertebra to the lower anal verge. Before the CT scans, patients were instructed to fill their bladders and take the Gastrografin solution (500 mL) to better visualize the small bowel. CT simulation images were imported into the Pinnacle 9.0 treatment planning system (Philips Radiation Oncology, Fitchburg, Wisconsin, USA) and named “plan CT”. Next, the target volume was delineated, and the treatment was planned. After verification, the treatment plan was delivered to the patients on the Synergy accelerator (Elekta, Elekta Oncology Systems, Crawley, UK). CT scans were repeated under the same conditions on Fridays of the 1st–4th weeks of treatment and named 1W, 2W, 3W, and 4W, respectively.
5
Multimodal Neuroimaging Protocol
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In the present study, the CT used was an Emotion Duo device and the MRI was performed with a Siemens device with 1 and 1.5 Tesla. The CT scan was performed with contrast-medium, the MRI was conducted native.
6
X-ray CT Imaging Protocol for Anatomical Scans
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For anatomical imaging, the CT images were acquired in the form of a digital imaging and communications in medicine stack using an x-ray CT (Emotion Duo, Siemens Medical Systems, Erlangen, Germany) system. The CT stack consisted of 110 axial slices of 512 × 512 pixels (0.14 mm × 0.14 mm), with 1-mm slice thickness. The x-ray CT source was operated at 110 kV and 76 mA with 1500-ms exposure time for each of the 110 acquired projections.
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