Philanthotoxin

Manufactured by Bio-Techne

Sourced in United States

Philanthotoxin is a potent neurotoxin isolated from the venom of the digger wasp Philanthus triangulum. It functions as a non-competitive antagonist of nicotinic acetylcholine receptors, which are involved in neuromuscular transmission. Philanthotoxin is commonly used in scientific research to study the structure and function of these receptors.

Automatically generated - may contain errors

Lab products found in correlation

Bicuculline, by Bio-Techne (2 mentions) Salts and general reagents, by Merck Group (2 mentions) Rp br camp, by Bio-Techne (2 mentions) Thapsigargin, by Bio-Techne (2 mentions) Forskolin, by Bio-Techne (2 mentions) Kainate, by Bio-Techne (2 mentions) Ryanodine, by Bio-Techne (2 mentions) Pertussis toxin, by Bio-Techne (1 mentions)

2 protocols using philanthotoxin

Pharmacology of Neurotransmitter Signaling

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Salts and general reagents were purchased from Sigma (St. Louis, MO, USA); GYKI 53655, D-AP5, NBQX, bicuculline, Rp-Br-cAMP, H-89, forskolin, philanthotoxin, ryanodine, thapsigargin, kainate, Pertussis toxin, CMZ and W-7 were obtained from Tocris (Bristol, UK).

Falcón-Moya R., Losada-Ruiz P, & Rodríguez-Moreno A. (2019). Kainate Receptor-Mediated Depression of Glutamate Release Involves Protein Kinase A in the Cerebellum. International Journal of Molecular Sciences, 20(17), 4124.

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Comprehensive Neuropharmacological Reagents

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Salts and general reagents were purchased from Sigma (St. Louis, MO, USA); GYKI 53655, D-AP5, NBQX, bicuculline, Rp-Br-cAMP, H-89, forskolin, philanthotoxin, ryanodine, thapsigargin, kainate, Pertussis toxin CMZ and W-7 were obtained from Tocris (Bristol, UK).

Falcón-Moya R., Losada-Ruiz P., Sihra T.S, & Rodríguez-Moreno A. (2018). Cerebellar Kainate Receptor-Mediated Facilitation of Glutamate Release Requires Ca2+-Calmodulin and PKA. Frontiers in Molecular Neuroscience, 11, 195.

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