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Hyaluronic acid

Manufactured by Sanofi

Hyaluronic acid is a naturally occurring polysaccharide found in various tissues of the body. It is a key component of the extracellular matrix and plays an important role in maintaining the structural integrity and hydration of tissues. As a laboratory product, hyaluronic acid is used as a versatile biomaterial for a wide range of applications, including tissue engineering, wound healing, and drug delivery.

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3 protocols using hyaluronic acid

1

Biomimetic Hydrogel Synthesis and Characterization

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Hyaluronic acid (60,000 Da, Genzyme Corporation, Cambridge, MA). Adipic dihydrazide, NHS-acrylate, acryloyl chloride, triethylamine, N-boc-ethylenediamine, 4-(4,6-dimethoxy[1 (link),3 (link),5 (link)]triazin-2-yl)-4-methylmorpholinium chloride (DMTMM), vanillin, potassium carbonate, ethyl-4-bromobutyrate, dimethylformamide (DMF), nitric acid, ethanol, sulfuric acid, trifluoroacetic acid, methanol, and acetic acid were purchased from Fisher Scientific and used without purification. Picoline borane complex and PEG dithiol (MW 1000 Da) were purchased from Sigma Aldrich and used without purification. Ac-FKGGGERC-NH2 (K peptide), Ac-GCRDGPQGIWGQDRCG-NH2, NQEQVSPLRGDSPGNH2 (Q-RGD peptide), and FITC-labeled NQEQVSPLRGDSPG-NH2 were purchased from Genscript (Piscataway, NJ) and used without purification. 4-arm PEG-vinylsulfone (PEG-VS, MW 40kDa) and 4-arm PEG-maleimide (PEG-MAL, MW 20kDa) were purchased from JenKem Inc. and used without further purification.
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2

Hyaluronic Acid Functionalization Protocol

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Hyaluronic acid (60,000 Da, Genzyme, Cambridge, MA) was functionalized as previously described13 (link).
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3

Hyaluronic Acid Functionalization Protocol

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Hyaluronic acid (60,000 Da, Genzyme, Cambridge, MA) was functionalized as previously described13 (link).
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